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Related Experiment Video

Updated: Jul 10, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

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Published on: June 2, 2014

Predictive model for the Migraine-ACT questionnaire in primary care.

Julio Pascual1, Miguel J A Láinez, Vicente Baos

  • 1Neurology Service, Hospital Universitario de Salamanca, Spain.

Current Medical Research and Opinion
|October 31, 2007
PubMed
Summary

The Migraine Assessment of Current Therapy (Migraine-ACT) questionnaire effectively identifies patients needing improved migraine treatment. This tool accurately predicts treatment success and monitors effectiveness in primary care settings.

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Area of Science:

  • Neurology
  • Clinical Research
  • Patient-Reported Outcomes

Background:

  • Migraine management is often suboptimal, leading to under-treatment.
  • The Migraine Assessment of Current Therapy (Migraine-ACT) is a patient-friendly tool designed to identify individuals who may benefit from adjustments to their acute migraine treatment.

Purpose of the Study:

  • To develop and validate a predictive model for the Migraine-ACT questionnaire within a primary care context.
  • To assess the questionnaire's utility in identifying patients requiring changes in migraine therapy.

Main Methods:

  • A prospective, open-label study involving 3272 patients across 1100 primary care sites.
  • Predictive validity was assessed using logistic regression, adjusting for multiple clinical and demographic factors.
  • The Migraine-ACT questionnaire's performance was evaluated in predicting treatment changes and patient satisfaction over a 3-month period.

Main Results:

  • Treatment was altered for 72% of patients, with overall satisfaction increasing from 15% to 49% after 3 months.
  • The predictive model demonstrated 86% sensitivity and 85% specificity in detecting a ≥1-point change in Migraine-ACT scores.
  • The model showed 77% sensitivity and 95% specificity in predicting improved patient satisfaction among those with a Migraine-ACT score improvement.

Conclusions:

  • The Migraine-ACT questionnaire is a validated, sensitive, and specific tool for predicting treatment outcomes in migraine patients.
  • It serves as a valuable instrument for detecting suboptimal migraine management and monitoring treatment efficacy in primary care.
  • The questionnaire aids in identifying patients who would benefit from adjustments to their migraine treatment regimen.