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Updated: Jul 10, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Pharyngeal pH monitoring in infants with laryngitis
Seckin O Ulualp1, Sarah Rodriguez, Samuel Cunningham
1Pediatric Airway and Swallowing Disorders Laboratory, Division of Pediatric Otolaryngology and Department of Otolaryngology, UTMB Children's Hospital, University of Texas Medical Branch, Galveston, TX 77555-0521, USA. seulualp@utmb.edu
Insights
Pharyngeal acid reflux (PAR) is common in infants with laryngitis, even with treatment. Flexible laryngoscopy-guided pH monitoring reveals PAR not always detected by esophageal monitoring alone.
Area of Science:
- Pediatric Otolaryngology
- Gastroenterology
- Pediatric Pulmonology
Background:
- Laryngitis in infants can be associated with gastroesophageal reflux.
- Assessing pharyngeal acid reflux (PAR) in infants is challenging.
Purpose of the Study:
- To evaluate pharyngeal acid reflux (PAR) exposure using flexible laryngoscopy-guided pharyngeal pH monitoring in infants diagnosed with laryngitis.
Main Methods:
- A retrospective review of 10 infants with laryngitis who underwent pharyngoesophageal pH monitoring was conducted.
- Data collected included patient history, physical examination findings, and pH monitoring results.
Main Results:
- Pharyngeal acid reflux (PAR) was detected in 6 out of 10 infants.
- Acid exposure time in the pharynx ranged from 0.1% to 1.2%.
- Esophageal acid reflux was present in 9 infants, with pharyngeal pH monitoring providing additional diagnostic information.
Conclusions:
- The majority of infants with laryngitis exhibited pharyngeal acid reflux (PAR).
- Esophageal acid reflux does not always extend to the pharynx.
- Pharyngeal pH monitoring offers valuable insights beyond standard esophageal monitoring for infants with laryngitis.
Objective:
To assess pharyngeal acid reflux (PAR) exposure with flexible laryngoscopy-guided pharyngeal pH monitoring in infants with laryngitis.
Study Design:
Tertiary care children's hospital.
Subjects And Methods:
Charts of 10 infants with laryngitis who underwent pharyngoesophageal pH monitoring were reviewed. Data included history, physical examination, and pharyngoesophageal pH monitoring findings.
Results:
Six infants had PAR. Two patients were on acid suppressive therapy and exhibited PAR. The number of PAR observed in six infants ranged between 1 and 81. The percent acid exposure time (AET) in the pharynx was between 0.1% and 1.2%. Esophageal acid reflux documented in nine infants ranged between 5 and 173. The percent AET in the esophagus was between 0.1% and 4.8%.
Conclusions:
The majority of the studied infants with laryngitis had PAR. Not all esophageal acid reflux reached the pharynx. Pharyngeal pH monitoring provides additional information that cannot be obtained with esophageal pH monitoring in infants with laryngitis.
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