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Related Experiment Video

Updated: Jul 10, 2026

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

Published on: May 31, 2024

Vessel-encoded arterial spin-labeling using pseudocontinuous tagging.

¹Department of Radiology, University of California, San Diego, La Jolla, CA, USA. ecwong@ucsd.edu

Magnetic Resonance in Medicine

|October 31, 2007

Summary

This summary is machine-generated.

A novel pseudocontinuous arterial spin labeling method enhances signal-to-noise ratio for precise brain vascular territory mapping. This technique improves separation of major arteries like the carotid and basilar, offering high-quality maps efficiently.

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Last Updated: Jul 10, 2026

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Published on: June 13, 2019

Area of Science:

Neuroimaging
Medical Physics
Vascular Biology

Background:

Accurate mapping of cerebral vascular territories is crucial for diagnosing and managing cerebrovascular diseases.
Conventional arterial spin labeling (ASL) techniques can be limited by signal-to-noise ratio (SNR) and spatial resolution.
Distinguishing between different arterial supplies, such as carotid and basilar territories, remains a challenge.

Purpose of the Study:

To introduce a novel, SNR-efficient method for mapping vascular territories using pseudocontinuous arterial spin labeling (ASL).
To improve the separation and visualization of individual cerebral vascular territories.
To achieve high-quality vascular territory maps within a clinically feasible scan time.

Main Methods:

Modification of the pseudocontinuous tagging pulse train with transverse gradient pulses and phase cycling.
Application of Hadamard or similar encoding schemes to optimize vessel tagging and relaxation.
Direct measurement of relative tagging efficiency from ASL data for decoding vascular territories.
Acquisition of high SNR maps of left carotid, right carotid, and basilar territories.

Main Results:

The developed method significantly enhances SNR for vascular territory mapping.
Improved separation and clear delineation of left carotid, right carotid, and basilar arterial territories were achieved.
High-quality vascular territory maps were generated in a short scan time of 6 minutes.

Conclusions:

The proposed SNR-efficient pseudocontinuous ASL method provides accurate and rapid mapping of cerebral vascular territories.
This technique offers a valuable tool for clinical neuroimaging and research in cerebrovascular disorders.
The improved SNR and separation capabilities represent a significant advancement in ASL-based vascular imaging.