Treatment characteristics in elderly asthmatics

In this study, we evaluated the effect of ageing on treatment response by comparing two groups of patients with asthma. All asthmatic patients in the study were assessed on repeated occasions once admitted to the hospital: soon after admission (0 h), and then at 5th, 10th, 24th, 48th, 72nd hour, 7th day and in stable period. We compared two groups of patients: younger asthmatics, which had 33 younger aged <60, and elderly asthmatics, comprised of 29 elderly aged >or=60 years. The Asthma Quality of Life Questionnaire (AQLQ) was used to assess health-related quality of life in study. The increases in FEV1% values observed soon after the hospital admission (0 h), and at 5th, 10th, 24th, 48th, 72nd hour, 7th day and in stable period in younger group were similar that in elderly group. The Borg scores observed soon after the hospital admission (0 h), and 5th, 10th, 24th, 48th and 72nd hour in elderly asthmatics was usually higher than that in younger asthmatics. However, symptom scores observed in elderly asthmatics soon after the hospital admission and at 72nd hour were higher than those in younger asthmatics. Furthermore, decreases in the total AQLQ score and asthma severity score from exacerbation to stable period in both asthmatics were not different. Present study indicated that the airways obstruction, AQLQ and other diseases characteristics of younger and elderly asthmatics could improve at similar rates with treatment. In addition, similar exacerbation severity in elderly asthmatics was perceived more intense than younger asthmatics.