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Human umbilical cord as a possible source of progesterone
R Gunasegaram1, K L Peh, A Loganath
1Institute of Science and Forensic Medicine, National Blood Centre, Singapore.
Biology of the Neonate
|January 1, 1991
Abstract:
Homogenates of human term umbilical cord were incubated with 7n-3H-pregnenolone. Using a reverse-isotope dilution technique, 3H-progesterone was isolated and characterized. The extent of enzymic conversion ranged from 2.5 to 55.4%. The results indicate that the cord can be a source of progesterone during human pregnancy.