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Related Concept Videos

Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012 for this...
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Regulating reprogenetics: strategic sacralisation and semantic massage.

Robin Mackenzie1

  • 1Kent Law School, University of Kent, Canterbury CT2 7NS, UK. r.mackenzie@kent.ac.uk

Health Care Analysis : HCA : Journal of Health Philosophy and Policy
|November 1, 2007
PubMed
Summary

Feminist critiques reveal how biomedicine excludes women's bodies in reprogenetic technology development. Strategic use of "sacred" notions creates consensus by marginalizing dissent, necessitating a symbolic order renegotiation.

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Last Updated: Jul 10, 2026

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Area of Science:

  • Feminist bioethics
  • Sociology of science and technology
  • Reprogenetics regulation

Background:

  • Biomedicine often systematically excludes the role of women's bodies in developing reprogenetic technologies.
  • Existing regulatory frameworks may be influenced by rhetoric that marginalizes women's perspectives.

Purpose of the Study:

  • To analyze how notions of the sacred are strategically used to shape consensus in reprogenetic technology regulation.
  • To critique the exclusionary discourse in reprogenetics and advocate for a renegotiation of the symbolic order.

Main Methods:

  • Feminist critique of regulatory consequences in biomedicine.
  • Analysis of strategic rhetoric in infertility treatment and embryo research regulation (UK).
  • Drawing on cultural anthropology of biomedicine and feminist ethnographies of reprogenetics.

Main Results:

  • The "sacred" is employed to decontextualize and delimit disagreement, fostering marginalization.
  • Conceptions of the sacred facilitate pragmatic regulatory consensus through symbolic manipulation.
  • A "bricolage" of culturally resonant images is used to solidify support or exclude dissenting views.

Conclusions:

  • An explicit renegotiation of the symbolic order is necessary to disrupt exclusionary dominant discourse in reprogenetics.
  • Challenging the strategic use of "sacred" notions can enrich and diversify debates on reprogenetic regulation.
  • Integrating feminist perspectives is crucial for a more inclusive and equitable approach to reprogenetic technologies.