Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global Consensus on the Management of Primary Localized Chordoma.

JAMA oncology·2026
Same author

PARP7 inhibitors enhance the immunogenic effects of radiation in pancreatic cancer cells.

Molecular therapy. Oncology·2026
Same author

Advancing Particle Therapy to Improve Cancer Care: Report on "2nd World Forum on Particle Therapy".

International journal of particle therapy·2026
Same author

Clinical White Paper From the "Hadrontherapy for Life" Symposium-Clinical Expansion of Carbon Ion Facilities Worldwide.

International journal of particle therapy·2026
Same author

Radiobiology Contributions and Perspectives in Hadron Therapy, With a Focus on Carbon Ions: Report From the Workshop Hadron Therapy for Life, Caen, March 2025.

International journal of particle therapy·2026
Same author

Impact of dose and dose-averaged linear energy transfer on oro-pharyngeal-mucosal toxicity in patients with non-squamous head and neck cancers treated with carbon-ion radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2025

Related Experiment Video

Updated: Jul 10, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Current concepts on imaging in radiotherapy.

Michela Lecchi1, Piero Fossati, Federica Elisei

  • 1Institute of Radiological Sciences, University of Milan, Milan, Italy.

European Journal of Nuclear Medicine and Molecular Imaging
|November 1, 2007
PubMed
Summary
This summary is machine-generated.

Advanced imaging techniques enhance high-precision radiotherapy (RT) by improving tumor delineation and guiding treatment. Positron emission tomography (PET) and image-guided RT (IGRT) offer functional insights and precise targeting for better patient outcomes.

More Related Videos

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Related Experiment Videos

Last Updated: Jul 10, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
10:48

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

  • Medical Physics
  • Oncology
  • Radiotherapy Technology

Background:

  • High-precision radiotherapy (RT) techniques like intensity-modulated radiation therapy (IMRT) and hadrontherapy offer improved dose distribution and normal tissue sparing compared to conventional RT.
  • Accurate tumor volume delineation, characterization, target localization, and motion monitoring are critical for these advanced RT techniques.
  • Current RT relies heavily on imaging technologies for these crucial tasks.

Purpose of the Study:

  • To examine the evolving role of imaging technologies throughout the high-precision radiotherapy process.
  • To highlight how advanced imaging aids in tumor delineation, characterization, and treatment delivery.
  • To discuss the integration of functional imaging and image guidance in modern RT.

Main Methods:

  • Review of current imaging modalities used in high-precision RT, including computed tomography (CT), magnetic resonance imaging (MRI), ultrasonography (US), and positron emission tomography (PET).
  • Discussion of the application of PET for evaluating tumor metabolism, proliferation, apoptosis, hypoxia, and angiogenesis.
  • Exploration of combined PET/CT systems for fused anatomical and functional data and the emerging field of image-guided radiotherapy (IGRT) with systems like cone beam CT and US.

Main Results:

  • Positron emission tomography (PET) provides crucial functional and molecular information for RT treatment planning, enhancing tumor characterization.
  • Combined PET/CT systems offer fused datasets for improved tumor volume delineation and treatment plan optimization.
  • Image-guided radiotherapy (IGRT) systems, including cone beam CT and US, are expanding, improving daily target localization and treatment monitoring.

Conclusions:

  • Imaging technologies are indispensable for the success of high-precision radiotherapy, from initial planning to treatment delivery and monitoring.
  • The integration of functional imaging (PET) and image guidance (IGRT) represents a significant advancement in optimizing RT efficacy and reducing patient morbidity.
  • Continued development and application of advanced imaging techniques are essential for the future of precision cancer treatment.