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Published on: October 17, 2013
Idiopathic slow transit constipation is rare. But delayed passage of meconium is common in the constipation clinic
G D H Croaker1, R Pearce, J Li
1The Canberra Hospital, Garran, ACT, 2605, Australia. croakers@netspeed.com.au
Insights
Constipated children frequently experience delayed meconium passage, suggesting congenital gut motility issues, not social deprivation. Idiopathic slow transit constipation is rare in these pediatric cases.
Area of Science:
- Pediatric Gastroenterology
- Colorectal Surgery
- Neonatology
Background:
- Constipation is a common pediatric issue.
- Congenital gut motility disorders are suspected in some resistant cases.
- Social deprivation is a hypothesized contributing factor.
Purpose of the Study:
- To investigate the link between childhood constipation and social deprivation.
- To identify congenital gut motility problems, including slow transit constipation (STC), in children with resistant constipation.
- To evaluate the utility of nuclear colon transit studies in diagnosing STC.
Main Methods:
- Retrospective audit of 140 children diagnosed with constipation.
- Nuclear colon transit studies were offered to 26 children with suspected congenital causes.
- Analysis of demographic data, meconium passage, and transit study results.
Main Results:
- Delayed meconium passage was significantly more common in constipated children (P << 0.001).
- Of 14 performed transit studies, 7 showed recto-sigmoid hold-up and 3 showed proximal slow transit.
- No significant association was found between childhood constipation and social class.
Conclusions:
- Delayed meconium passage is a significant indicator in pediatric constipation, pointing towards congenital gut motility issues.
- Idiopathic slow transit constipation is rare, and congenital causes are more prevalent in this cohort.
- Social deprivation does not appear to be a significant factor in childhood constipation.
Abstract:
We hypothesise that constipated children would be more likely to come from a socially deprived background. We also hypothesise that a percentage of children with resistant constipation would have a congenital gut motility problem that might be recognised at birth, and that some of these would have slow transit constipation that could be recognised on nuclear transit study. One hundred and forty children with a constipation related diagnosis were seen in the last 4 years, and were reviewed as a retrospective audit. Twenty-six children who were felt likely to have a congenital cause for their constipation were offered nuclear colon transit study to search for slow transit constipation. One hundred and forty children from the constipation clinic were reviewed. There were 67 females (47.9%) and 73 males (52.1%), a sex ratio near equality. The mean age at presentation was 5.38 years. Forty-one percent were formally discharged, 36% were lost to follow up, and 23% are still being seen. There was a highly significant tendency for these children to have delayed passage of meconium, as compared normal newborns (P << 0.001). Twenty-six children were considered for possible transit study, and 14 were performed. Four of these were normal, seven showed hold up in the recto-sigmoid, and three showed more proximal slow transit. Two of these probably have non ISTC diagnoses. Social class seems similar to the general population on the criterion employed. Delayed passage of meconium in this group was significantly more frequent than in the general population, but only one of the group seems likely to have truly idiopathic slow transit constipation, and he did not have delayed passage of meconium. There is no evidence for an effect of social class in this population. Idiopathic slow transit constipation itself is rare.
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