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Related Experiment Videos

Assessing the risks of extended wear.

W J Benjamin

    Optometry Clinics : the Official Publication of the Prentice Society
    |January 1, 1991
    PubMed
    Summary
    This summary is machine-generated.

    Extended contact lens wear poses significant risks, with complication rates reaching 31%. Extended wear of hydrogel lenses increases ulcerative keratitis risk 4.2 times compared to daily wear.

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    Area of Science:

    • Ophthalmology
    • Public Health
    • Biomedical Engineering

    Background:

    • Contact lens wear is associated with varying risks of ocular complications.
    • Existing literature lacks a comprehensive overview of contact lens-related risks.
    • Understanding these risks is crucial for patient safety and eye care practices.

    Purpose of the Study:

    • To conduct a meta-analysis to comprehensively assess contact lens wear complications.
    • To quantify the incidence and severity of specific risks, particularly ulcerative keratitis.
    • To compare risks between daily wear and extended wear, and between hydrogel and rigid lens types.

    Main Methods:

    • Meta-analysis of complication data from multiple sources.
    • Inclusion of data from contact lens package inserts, non-referral extended wear, emergency room visits, referral corneal ulceration, and comparative daily vs. extended wear studies.

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  • Calculation of complication and corneal ulceration rates for different lens types and wear schedules.

    • Main Results:

    • Total complication rates for extended wear (rigid and hydrogel) ranged from 7% to 31% over 12-22 months.
    • Mean annual corneal ulceration rates were 0.44% for hydrogel extended wear and 0.21% for rigid extended wear.
    • Hydrogel extended wear increased ulcerative keratitis risk 4.2-fold compared to hydrogel daily wear; rigid extended wear had half the risk of hydrogel extended wear.

    Conclusions:

    • Extended contact lens wear, particularly with hydrogel lenses, significantly elevates the risk of ulcerative keratitis.
    • Rigid gas permeable lenses appear to offer a lower risk profile for extended wear compared to hydrogels.
    • Estimated over 71,000 annual cases of ulcerative keratitis in the US highlight a substantial public health concern for contact lens wearers.