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A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Effect of mandibular distraction osteogenesis on developing molars.
M Kleine-Hakala1, J Hukki, K Hurmerinta
1Department of Plastic Surgery, Helsinki University Central Hospital, Helsinki, Finland. kleinehakala@yahoo.com
Orthodontics & Craniofacial Research
|November 2, 2007
Summary
Mandibular distraction osteogenesis (DO) can affect developing molars, causing root malformations and hindered tooth development in some pediatric patients. Careful consideration of device type and timing is advised to mitigate these dental injuries.
Area of Science:
- Craniofacial surgery
- Pediatric dentistry
- Orthodontics
Background:
- Mandibular distraction osteogenesis (DO) is a surgical procedure to correct severe retrognathia.
- DO is frequently used in children with craniofacial syndromes.
- The impact of DO on developing dentition requires further investigation.
Purpose of the Study:
- To evaluate the effects of mandibular DO on the development of permanent mandibular molars.
- To identify the types and prevalence of dental anomalies resulting from DO.
Main Methods:
- A descriptive clinical study was conducted on 17 children with craniofacial syndromes.
- Patients underwent mandibular DO using an extraoral device.
- Panoramic tomograms were analyzed retrospectively after a mean follow-up of 3.6 years.
Main Results:
- DO affected developing mandibular molars in 13 of 17 patients (76%).
- Observed dental injuries included root malformations, hindered development, follicle destruction, and positional changes.
- Tooth follicle injury during osteotomy or pin placement, and germ migration were primary causes.
Conclusions:
- Dental injuries are a recognized complication of mandibular DO in children.
- While DO offers significant benefits, the potential for dental harm necessitates careful device selection and procedural timing.
- Further research may refine DO techniques to minimize dental sequelae.
