Related Experiment Video
Updated: Jul 10, 2026
09:11
A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
[Chlamydia trachomatis infection in newborn infants]
Srpski Arhiv Za Celokupno Lekarstvo
|September 1, 1995
Summary
Chlamydia trachomatis infections in newborns can be detected by specific antibodies. This study found higher rates of Chlamydia trachomatis-specific IgM antibodies in newborns with low birth weight.
Area of Science:
- Neonatal immunology
- Infectious diseases
- Pediatric health
Context:
- Chlamydia trachomatis is a common sexually transmitted bacterium.
- Neonatal infections can lead to significant health complications.
- Antibody detection is a key method for diagnosing infections in newborns.
Purpose:
- To determine the prevalence of Chlamydia trachomatis infection in newborns using antibody detection.
- To investigate the association between Chlamydia trachomatis antibodies, Apgar scores, and birth weight in neonates.
Summary:
- This study tested 52 newborn infants for Chlamydia trachomatis antibodies.
- High serum IgG titers were found in 21% and high IgM titers in 17% of newborns.
- A statistically significant correlation was observed between Chlamydia trachomatis-specific IgM antibodies and low birth weight (<2500 g).
Impact:
- Highlights a potential link between Chlamydia trachomatis infection and adverse birth outcomes.
- Suggests the importance of screening for Chlamydia trachomatis in at-risk newborns.
- Informs clinical practice regarding the management and prevention of neonatal Chlamydia infections.
Related Concept Videos
01:29Bacterial Phylum Chlamydiae
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic of...
01:26Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
01:18Trichomoniasis
Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
01:28Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
01:27Cytomegalovirus Disease
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
01:22American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...