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Updated: Jul 10, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Total knee arthroplasty for isolated patellofemoral arthritis in younger patients
John B Meding1, Jennifer T Wing, E Michael Keating
1The Center for Knee and Hip Surgery, Mooresville, IN 46158, USA. jmeding@msn.com
Unlabelled:
Are the results of total knee arthroplasty for isolated patellofemoral osteoarthritis (OA) in younger patients as good as with patellofemoral arthroplasty? We retrospectively compared the outcomes of 33 TKAs in 27 patients with patellofemoral OA younger than 60 years of age (average, 52 years) to those for a matched group of patients with primarily tibiofemoral arthritis. A cemented posterior cruciate ligament-retaining prosthesis was used in 26 of the 27 knees. We recorded the intraoperative condition of the cartilage. Patients were followed a minimum of 2 years (average, 6.2 years). Average Knee Society knee scores improved from 49 preoperatively to 88 at final followup. Average pain scores from 5 to 44 with 29 knees rated with minimal or no pain; two patients reported anterior knee pain. There were no infections, revisions, reoperations, manipulations, patellar instabilities, patellar fractures, or component loosenings. The results in these patients were as good as those for younger historical control patients undergoing patellofemoral arthroplasty and the complication rates lower. The data were similar to those for our matched group of patients with primarily tibiofemoral OA. We believe our data should raise doubts about the use of patellofemoral arthroplasty in any patient.
Level Of Evidence:
Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
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