Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Middle latency auditory evoked potentials in temporal lobe disorders.

W Shehata-Dieler1, H Shimizu, S M Soliman

  • 1Johns Hopkins Medical Institutions, Baltimore, Maryland.

Ear and Hearing
|December 1, 1991
PubMed
Summary

Middle latency auditory evoked potentials (MAEP) showed reduced amplitude and delayed latency in patients with temporal lobe lesions affecting auditory pathways. These findings aid in understanding auditory processing in the temporal lobe.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in urinary retinol binding protein excretion and other indices of renal tubular damage in patients with non-insulin dependent diabetes.

Diabetes research and clinical practice·1992
Same author

Entrainment to external Ca2+ oscillation in ionophore-treated Physarum plasmodium.

Cell structure and function·1992
Same author

Modulation of C2 and C3 gene expression of human peripheral blood monocytes by interleukin 1 beta, interferon gamma, tumor necrosis factor alpha and lipopolysaccharide.

Experientia·1992
Same author

Do pigmented naevi in albinism provide evidence of tyrosinase positivity?

The British journal of dermatology·1992
Same author

Dexamethasone attenuates altered insulin secretion elicited by interleukin-1 beta in HIT cells.

European journal of pharmacology·1992
Same author

Effect of dichloroacetate on recovery of brain lactate, phosphorus energy metabolites, and glutamate during reperfusion after complete cerebral ischemia in rats.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·1992

Area of Science:

  • Neuroscience
  • Audiology
  • Clinical Neurology

Background:

  • Middle latency auditory evoked potentials (MAEP) are used to assess auditory pathway function.
  • Temporal lobe lesions can impact auditory processing, but their specific effects on MAEP are not fully elucidated.

Purpose of the Study:

  • To investigate the impact of temporal lobe lesions on MAEP.
  • To identify specific MAEP alterations related to the location of temporal lobe lesions.
  • To discuss the generators of MAEP in humans.

Main Methods:

  • Recording MAEP in 30 normal subjects and 19 patients with temporal lobe lesions.
  • Comparing MAEP amplitude and latency between patient groups with different lesion locations.
  • Analyzing amplitude reduction and latency shifts in the Na-Pa component.

Related Experiment Videos

Main Results:

  • Significant reduction in Na-Pa amplitude observed in patients with lesions involving auditory areas or radiation.
  • Latency shifts in Pa were noted but were less pronounced than amplitude reductions.
  • Lesions not involving auditory structures did not show similar amplitude reductions.

Conclusions:

  • MAEP, particularly Na-Pa amplitude, is differentially affected by specific temporal lobe structures involved.
  • Clinical application of MAEP for diagnosing temporal lobe disorders is limited by intersubject variability and myogenic contamination.