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A clinical profile of multidrug resistant typhoid fever
S Mishra1, A K Patwari, V K Anand
1Department of Pediatrics, Lady Hardinge Medical College, New Delhi.
Indian Pediatrics
|October 1, 1991
Abstract:
Fifty blood culture positive patients of typhoid fever were studied during the current outbreak of the disease for their clinical profile. In 39 (78%) cases the isolates of S. typhi were resistant to conventional drugs. Children below 2 years of age constituted 20% of the total cases and belonged exclusively to the group with multidrug resistant typhoid fever (MRTF). The clinical presentation seemed to mimic malaria, bronchopneumonia, meningitis, etc. Typhoid hepatitis was diagnosed in 2 cases with MRTF. Life threatening complications were seen in 28.2% patients and were observed exclusively in MRTF group.