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Updated: Jul 10, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
A preschool-age child with first-time seizure and ataxia
1Department of Emergency Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Insights
Pediatric stroke can result from vertebral artery dissection, a condition often presenting with ataxia or seizure. Early recognition via advanced imaging is crucial for children with neurological symptoms.
Area of Science:
- Neurology
- Pediatric Neurology
- Vascular Neurology
Background:
- Cervical artery dissection accounts for up to 20% of childhood strokes.
- Pediatric dissections often lack the typical adult presentation of head and neck pain.
Observation:
- A 4-year-old experienced a seizure and was diagnosed with cerebellar ataxia.
- Initial CT scans were inconclusive, but later neuroimaging revealed a left vertebral artery dissection causing stroke.
Findings:
- Vertebral artery dissection can manifest as posterior circulation ischemia, leading to symptoms like ataxia, vomiting, vertigo, dysarthria, and seizures.
- This case highlights a child presenting with seizure and ataxia, ultimately diagnosed with vertebral artery dissection.
Implications:
- Advanced, non-invasive imaging can aid in the early detection of pediatric cervical artery dissection.
- Vertebral artery dissection should be considered in the differential diagnosis for children presenting with seizures, headache, or neck pain.
Abstract:
We present a case of a 4-year-old previously healthy child who had a possible first-time seizure at home, and upon a second Emergency Department evaluation was found to have gross cerebellar ataxia suggestive of acute stroke. Initial computed tomography scan and metabolic work-up were unrevealing. Subsequent neuroimaging demonstrated stroke in the left medulla and cerebellum secondary to left vertebral artery dissection. Cervical artery dissection may cause up to 20% of strokes in childhood and adolescence. Unlike typical adult presentations, antecedent or concurrent head and neck pain occurs less often in pediatric dissections. Symptoms of posterior circulation ischemia resulting from vertebral artery dissection may include vertigo, vomiting, ataxia, dysarthria, and seizure. Willingness to utilize newer, non-invasive imaging modalities may lead to earlier recognition of cervical artery dissection when patients have prodromal symptoms or episodes of transient ischemia. Vertebral artery dissection should be included in the differential diagnosis when evaluating children with first time seizure, headache, or neck pain.
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