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Cerebral venous thrombosis: a case report
Nishant Anand1, Carmie Chan, N Ewen Wang
1Stanford Kaiser Emergency Medicine Residency Program, Stanford, California, USA.
Insights
Cerebral venous thrombosis (CVT) affects adults and children, often presenting with severe headaches. While treatment options vary, earlier diagnosis is improving patient outcomes for this rare condition.
Area of Science:
- Neurology
- Vascular Medicine
Background:
- Cerebral venous thrombosis (CVT) is a rare condition with an incidence of 3-4 per million adults and 7 per million children.
- CVT can present with diverse neurological signs and symptoms, most commonly severe headache in adults.
Observation:
- A case of CVT in a 19-year-old woman with a history of migraines is presented.
- Frequently affected sinuses include the lateral, cavernous, and superior sagittal sinuses.
- Risk factors encompass prothrombotic conditions, pregnancy, and the peripartum period.
Findings:
- Computed tomography may reveal the "delta sign," while MRI with MR venography offers higher sensitivity for diagnosis.
- Current treatment strategies, including anticoagulation, fibrinolysis, mechanical thrombectomy, and surgery, remain a subject of debate.
Implications:
- Despite controversial management, the prognosis for CVT has improved due to increased diagnostic frequency.
- Early and accurate diagnosis of CVT is crucial for better patient outcomes.
Abstract:
The incidence of cerebral venous thrombosis (CVT) is three to four cases per one million in adults and seven cases per one million among children. We discuss a case of CVT in a 19-year-old woman with a history of migraine headaches. A CVT most commonly presents acutely, with a wide variety of signs and symptoms in young adults and children. The most common presenting complaint in adults is severe headache. The most frequently thrombosed sinuses are the lateral, cavernous, and superior sagittal sinuses. Risk factors include any genetic or acquired prothrombotic conditions, including pregnancy and the peripartum period. Computed tomography may show the classic "delta sign," although magnetic resonance imaging with magnetic resonance venography is more sensitive. Treatment is controversial at this time. Options include fibrinolysis, anticoagulation, mechanical thrombectomy, or surgery. Despite the lack of agreement on management of CVT, the prognosis of CVT has improved, due to an increasing frequency of diagnosis.
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