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[Stroke in young adults with celiac disease]
1Service de médecine interne et maladies systémiques, CHU de Dijon, hôpital Général, 3, rue du Faubourg-Raines, 21000 Dijon, France. sylvain.audia@u-bourgogne.fr
La Revue De Medecine Interne
|November 3, 2007
Summary
Celiac disease (an autoimmune disorder) can manifest as stroke in young adults. Consider celiac disease in unexplained young adult strokes, especially with hyperhomocysteinemia or antiphospholipid syndrome.
Area of Science:
- Neurology
- Gastroenterology
- Immunology
Background:
- Celiac disease affects approximately 1% of the population.
- Extradigestive symptoms are common, including neurological manifestations.
- Stroke is a recognized, though less common, neurological presentation of celiac disease.
Observation:
- Two cases of young adults experiencing stroke were diagnosed with celiac disease.
- Case 1 involved hyperhomocysteinemia and cerebral arterial vasculopathy.
- Case 2 was associated with antiphospholipid syndrome.
Findings:
- These findings highlight a potential link between celiac disease and stroke in young adults.
- Specific conditions like hyperhomocysteinemia and antiphospholipid syndrome may contribute to stroke pathogenesis in celiac patients.
- Celiac disease should be considered in the differential diagnosis of unexplained strokes in this demographic.
Implications:
- Early diagnosis of celiac disease can be crucial for managing stroke risk.
- Further research is warranted to elucidate the mechanisms connecting celiac disease and cerebrovascular events.
- This underscores the importance of a multidisciplinary approach in diagnosing and treating complex cases.
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