Use of natural surfactant in an infant with aspiration syndrome

M Bisceglia1, M Verre, F Tancioni

  • 1Department of Neonatology Intensive Care Unit, S. Giovanni di Dio Hospital, Crotone, Italy. m.bisceglia@tin.it

Minerva Pediatrica
|November 6, 2007
PubMed

Insights

Porcine surfactant (Curosurf) successfully treated acute respiratory distress syndrome (ARDS) in an 18-month-old child following gastric juice inhalation. This highlights surfactant therapy

Area of Science:

  • Pulmonology
  • Critical Care Medicine
  • Pediatric Respiratory Medicine

Background:

  • Surfactant therapy is established in neonatal respiratory distress.
  • Pulmonary pathophysiology suggests potential benefits in non-neonatal populations.
  • Acute Respiratory Distress Syndrome (ARDS) presents significant respiratory challenges.

Observation:

  • An 18-month-old child presented with ARDS.
  • The ARDS was caused by asphyxiation due to gastric juice inhalation.
  • Standard ventilatory therapy was initiated.

Findings:

  • The child received porcine surfactant (Curosurf) as an adjunct therapy.
  • The combination of surfactant and ventilatory support led to successful treatment.
  • This case demonstrates the efficacy of surfactant in pediatric ARDS.

Implications:

  • Surfactant therapy may be a viable treatment option for pediatric ARDS beyond neonatal indications.
  • This approach could improve outcomes for children with severe respiratory failure.
  • Further research into surfactant use for ARDS in children is warranted.

Related Concept Videos

Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned under...
Suctioning the Oropharyngeal Airway01:25

Suctioning the Oropharyngeal Airway

In preparing for oropharyngeal airway suctioning, a nurse must gather all necessary equipment, including a suction unit with tubing, a prepackaged suction kit, sterile gloves, water or saline for irrigation, a water-soluble lubricant, and additional personal protective equipment (such as a gown, mask, and goggles) to control infections.
After assembling the equipment, the nurse should practice hand hygiene and don appropriate PPE according to infection control guidelines to avoid the...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...