Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Comparing the Survival Analysis of Two or More Groups01:20

Comparing the Survival Analysis of Two or More Groups

Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and Cox...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rivaroxaban versus aspirin for secondary prevention of ischaemic stroke in patients with cancer: a subgroup analysis of the NAVIGATE ESUS randomized trial.

European journal of neurology·2020
Same author

Self-reported psychosis-like experiences in patients with mood disorders.

European psychiatry : the journal of the Association of European Psychiatrists·2017
Same author

Long-term mortality and causes of death in endoscopically verified upper gastrointestinal bleeding: comparison of bleeding patients and population controls.

Scandinavian journal of gastroenterology·2017
Same author

Mediating role of borderline personality disorder traits in the effects of childhood maltreatment on suicidal behaviour among mood disorder patients.

European psychiatry : the journal of the Association of European Psychiatrists·2017
Same author

Level of functioning, perceived work ability, and work status among psychiatric patients with major mental disorders.

European psychiatry : the journal of the Association of European Psychiatrists·2017
Same author

Randomized clinical trial comparing surgery, endovenous laser ablation and ultrasound-guided foam sclerotherapy for the treatment of great saphenous varicose veins.

The British journal of surgery·2016

Related Experiment Video

Updated: Jul 10, 2026

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
14:18

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat

Published on: August 30, 2020

Lower limb amputations: differences between the genders and long-term survival.

M Heikkinen1, J Saarinen, V P Suominen

  • 1Department of Surgery, University Hospital, Medical School, Tampere University, Tampere, Finland. mheik@netti.fi

Prosthetics and Orthotics International
|November 6, 2007
PubMed
Summary

Men experience higher amputation incidence than women, particularly for trauma-related amputations. Survival after amputation is similar between genders when age is considered, but diabetes negatively impacts survival for both sexes, especially men.

Related Experiment Videos

Last Updated: Jul 10, 2026

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
14:18

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat

Published on: August 30, 2020

Area of Science:

  • Vascular Surgery
  • Epidemiology
  • Public Health

Background:

  • Gender-based disparities in vascular disease outcomes are not fully understood.
  • Amputation remains a significant outcome in peripheral arterial disease and trauma.
  • Understanding differences in amputation incidence and survival by gender is crucial for targeted interventions.

Purpose of the Study:

  • To investigate gender-specific differences in amputation incidence.
  • To compare revascularization rates prior to amputation between men and women.
  • To analyze survival outcomes following amputation stratified by gender.

Main Methods:

  • Population-based study utilizing regional amputation data (1990-1999) and national death records.
  • Cross-linking of amputation and vascular registry data using unique patient identifiers.
  • Age-standardization and statistical analysis to compare incidence and survival between genders.

Main Results:

  • Men had a higher age-standardized amputation incidence (338/10^6) than women (226/10^6), with males showing over three-fold higher major trauma amputation incidence.
  • Women were older at the time of amputation (mean age difference 8 years).
  • Median survival after amputation was shorter for women (716 days) than men (943 days), but this difference disappeared after adjusting for age. Diabetes significantly worsened survival in both genders, particularly men.

Conclusions:

  • Amputation incidence is higher in men, especially for trauma, while women are older at the time of amputation.
  • After age adjustment, gender does not significantly impact survival post-amputation.
  • Diabetes is a significant independent risk factor for poorer survival following major amputation in both genders.