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[Syphilitic uveitis and human immunodeficiency virus infection].
V Bouisse1, I Cochereau-Massin, D Jobin
1Service d'Ophtalmologie, Hôpital de la Pitié-Salpétrière, Paris.
Journal Francais D'Ophtalmologie
|January 1, 1991
Summary
Ocular syphilis is rare but should be considered in HIV-infected patients with uveitis. Prompt diagnosis and high-dose penicillin treatment are crucial for co-infected individuals.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Neurology
Background:
- Ocular syphilis is uncommon in individuals with human immunodeficiency virus (HIV).
- Syphilis should be considered in HIV-infected patients presenting with uveitis.
Observation:
- Ocular syphilis often involves retinitis with uveitis and optic neuritis.
- Concurrent neurosyphilis is frequent and can be more aggressive in HIV-positive individuals.
Findings:
- Standard syphilis serological tests may be nonreactive in HIV-positive patients due to altered immune responses.
- Lumbar puncture is recommended for evaluating co-infected patients.
Implications:
- High-dose intravenous penicillin G is recommended for all co-infected patients, similar to neurosyphilis treatment.
- Early consideration and appropriate management of ocular syphilis in HIV patients are critical to prevent severe complications.