Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lipid Tail Length Determines Nano-Bio Interactions of Peptide Amphiphile Nanostructures.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Lipid Tail Length Determines Nano-Bio Interactions of Peptide Amphiphile Nanostructures.

bioRxiv : the preprint server for biology·2025
Same author

Multiplexed and Millimeter-Scale Fluorescence Nanoscopy of Cells and Tissue Sections via Prism-Illumination and Microfluidics-Enhanced DNA-PAINT.

Chemical & biomedical imaging·2023
Same author

Multispectral Localized Surface Plasmon Resonance (msLSPR) Reveals and Overcomes Spectral and Sensing Heterogeneities of Single Gold Nanoparticles.

ACS nano·2023
Same author

cyc-DEP: Cyclic immunofluorescence profiling of particles collected using dielectrophoresis.

Electrophoresis·2022
Same author

Electro-optical mechanically flexible coaxial microprobes for minimally invasive interfacing with intrinsic neural circuits.

Nature communications·2022

Related Experiment Video

Updated: Jul 10, 2026

From Fast Fluorescence Imaging to Molecular Diffusion Law on Live Cell Membranes in a Commercial Microscope
15:10

From Fast Fluorescence Imaging to Molecular Diffusion Law on Live Cell Membranes in a Commercial Microscope

Published on: October 9, 2014

Performance trade-offs in single-photon avalanche diode miniaturization.

Hod Finkelstein1, Mark J Hsu, Sanja Zlatanovic

  • 1Electrical and Computer Engineering Department, University of California, San Diego, 9300 Gilman Dr., M.S. 0407, La Jolla, California 92093-0407, USA.

The Review of Scientific Instruments
|November 6, 2007
PubMed
Summary

Miniaturized single-photon avalanche diodes (SPADs) offer faster performance but face challenges. A novel compact active-recharge scheme enhances signal-to-noise ratio, benefiting advanced imaging and quantum systems.

More Related Videos

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
11:27

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2

Published on: December 8, 2016

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Related Experiment Videos

Last Updated: Jul 10, 2026

From Fast Fluorescence Imaging to Molecular Diffusion Law on Live Cell Membranes in a Commercial Microscope
15:10

From Fast Fluorescence Imaging to Molecular Diffusion Law on Live Cell Membranes in a Commercial Microscope

Published on: October 9, 2014

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
11:27

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2

Published on: December 8, 2016

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Area of Science:

  • Photonics and Semiconductor Devices
  • Integrated Circuit Design

Background:

  • Single-photon avalanche diodes (SPADs) are crucial for precise photon timing.
  • Miniaturization of SPADs is pursued for large-array integration and reduced dead time.

Purpose of the Study:

  • To investigate the advantages and disadvantages of SPAD miniaturization.
  • To characterize a novel, compact SPAD in a commercial 0.18 microm CMOS technology.

Main Methods:

  • Characterization of a new fast SPAD with a novel guard ring design.
  • Evaluation of a compact active-recharge scheme for improved signal-to-noise ratio.

Main Results:

  • The developed SPAD achieves a record-low dead time of 5 ns.
  • Device miniaturization leads to a high after-pulsing rate, a limiting factor.
  • The new active-recharge scheme improves signal-to-noise by tenfold without increasing dead time.

Conclusions:

  • SPAD miniaturization presents trade-offs between speed and after-pulsing.
  • Compact active-recharge circuits are essential for optimizing performance in miniaturized SPADs.
  • These advancements benefit applications like fluorescence-lifetime imaging and quantum key distribution.