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Published on: April 3, 2026
[Meckel's diverticulum and gastrointestinal stromal tumor: an unusual association]
Felipe de la Morena López1, Luis Fernández-Salazar, Benito Velayos
1Servicio de Aparato Digestivo. Hospital Universitario de la Princesa. Madrid. España. felipe_de_la_morena@hotmail.com
Abstract:
Meckel's diverticulum is the most prevalent congenital abnormality of the gastrointestinal tract. Bleeding from Meckel's diverticulum is the most common clinical presentation, especially in childhood. In adults, manifestations include a broad spectrum of symptoms ranging from an incidental finding in surgery, iron deficiency anemia of unknown etiology, and acute abdomen due to mechanical complications of the diverticulum. Neoplastic transformation has been reported, but gastrointestinal stromal tumors are exceptional in this location. We report a case of gastrointestinal stromal tumor in Meckel's diverticulum, complicated by perforation.
Insights
Gastrointestinal stromal tumors are rare in Meckel
Area of Science:
- Gastroenterology
- Surgical Pathology
Background:
- Meckel's diverticulum is the most common congenital gastrointestinal abnormality.
- Clinical presentations vary widely, especially in adults, including anemia and acute abdomen.
Observation:
- This case highlights a rare instance of a gastrointestinal stromal tumor (GIST) within a Meckel's diverticulum.
- The GIST presented with a critical complication: perforation.
Findings:
- Gastrointestinal stromal tumors are exceptionally uncommon in Meckel's diverticula.
- Perforation represents a severe, though infrequent, complication of such tumors in this location.
Implications:
- This case underscores the importance of considering rare neoplastic complications in Meckel's diverticulum.
- Awareness of GISTs in Meckel's diverticulum is crucial for accurate diagnosis and management, particularly when complications arise.
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