Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Telomeres II.

Duncan M Baird1

  • 1Department of Pathology, Cardiff University, Heath Park, Cardiff, UK. bairddm@cardiff.ac.uk

Experimental Gerontology
|November 6, 2007
PubMed
Summary
This summary is machine-generated.

Telomere erosion, the shortening of protective caps on chromosomes, is increasingly linked to aging and age-related diseases. This review covers recent findings on telomere dysfunction mechanisms, age-related telomere loss, and inheritance patterns.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

TeloNet is born: why all specialities need to be aware of telomere biology disorders.

Frontiers in medicine·2026
Same author

Telomere Dysfunction and Proteostasis Decline Define Distinct Pathways of Cellular Senescence in the Human Respiratory Tract.

Aging cell·2026
Same author

Mitotic microhomology-mediated break-induced replication promotes chromoanasynthesis.

Nature communications·2026
Same author

GW: ultra-fast chromosome-scale visualization of genomics data.

Nature methods·2025
Same author

hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan.

Aging cell·2025
Same author

Clinical Use of ZSCAN4 for Telomere Elongation in Hematopoietic Stem Cells.

NEJM evidence·2025
Same journal

Ayurvedic nutraceutical, Chyawanprash, enhances longevity and stress resilience via mitochondrial and muscular health in C. elegans model of ageing.

Experimental gerontology·2026
Same journal

Activation of Sirt3 reprograms mitochondrial function to regenerate intervertebral disc degeneration.

Experimental gerontology·2026
Same journal

Sit-to-stand power shows greater magnitude associations with radial bone strength compared to handgrip strength in adults aged 60-95 years: A cross-sectional study.

Experimental gerontology·2026
Same journal

Impact of simultaneous motor-cognitive training on motor capacities in older adults: A quasi-randomized parallel controlled trial.

Experimental gerontology·2026
Same journal

Triglyceride-glucose-related metabolic indices, phenotypic aging, and incident pulmonary embolism.

Experimental gerontology·2026
Same journal

A comparative study reveals distinct patterns of resting-state activity in tinnitus and chronic pain.

Experimental gerontology·2026
See all related articles

Area of Science:

  • Gerontology and Molecular Biology
  • Cellular Aging Research

Background:

  • Telomere erosion is a significant factor in cellular aging.
  • Understanding telomere dynamics is crucial for comprehending age-related tissue changes.

Purpose of the Study:

  • To review recent research on telomeres and aging.
  • To highlight new findings on telomere dysfunction, age-related loss, disease associations, and inheritance.

Main Methods:

  • Review of selected papers published between July 2006 and June 2007.
  • Analysis of experimental evidence from mouse models.
  • Examination of associations between telomere length and age-related diseases.

Main Results:

  • Telomere dysfunction can compromise tissue homeostasis.

Related Experiment Videos

  • Evidence supports telomere loss as a function of age.
  • Telomere length is associated with age-related diseases.
  • New insights into telomere length inheritance were presented.

    • Conclusions:

    • Telomere erosion plays a critical role in the aging process.
    • Further research into telomere biology is essential for understanding and potentially mitigating age-related decline and disease.