A retrospective study on the coexistence of hydatid cyst and aspergillosis

Nazim Emrah Koçer1, Yasemin Kibar, Muhammed Emin Güldür

  • 1Department of Pathology, Faculty of Medicine, Baskent University, Ankara, Turkey. nemrahkocer@yahoo.com

Abstract

Insights

This study found a rare co-infection of aspergillosis and hydatid cyst in two lung cases. Histopathology is crucial for diagnosing this rare co-occurrence, especially in immunocompromised patients.

Area of Science:

  • Medical Mycology
  • Parasitology
  • Pathology

Background:

  • Hydatid cyst is an endemic zoonotic disease.
  • Aspergillosis, caused by Aspergillus fungus, presents various lung pathologies.
  • The co-infection of hydatid cyst and aspergillosis is exceptionally rare.

Purpose of the Study:

  • To investigate the coexistence of aspergillosis and echinococcosis in archival materials.
  • To discuss the potential clinical significance of this rare co-infection.

Main Methods:

  • Reevaluation of 100 archival hydatid cyst cases by four pathologists.
  • Application of Grocott's methenamine-silver (GMS) and periodic acid-Schiff (PAS) stains for suspected co-infections.

Main Results:

  • Two cases of coexisting aspergillosis and hydatid cyst were identified among 100 cases.
  • Both identified cases were located in the lung and occurred in immunocompetent patients.

Conclusions:

  • The coexistence of aspergillosis and hydatid cyst warrants attention, particularly in immunocompromised individuals or with cyst rupture.
  • Radiological imaging lacks reliable data for detecting Aspergillus within hydatid cysts.
  • Histopathological examination is essential for accurate diagnosis and management planning.

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