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Recurrent deep venous thrombosis during optimal anticoagulation and overt hyperthyroidism: a case report
Alessandro Squizzato1, Josè Vitale, Victor Ea Gerdes
1Department of Clinical Medicine, University of Insubria, Varese, Italy. alexsquizzo@libero.it
Summary
Recurrent deep venous thrombosis (DVT) can occur even with proper anticoagulant therapy. This case highlights overt hyperthyroidism as a potential risk factor for recurrent DVT in elderly patients.
Area of Science:
- Cardiology
- Endocrinology
- Hematology
Background:
- Recurrent deep venous thrombosis (DVT) despite anticoagulation is clinically significant.
- Overt hyperthyroidism is a potential, though less common, contributor to thromboembolic risk.
Observation:
- An elderly male patient experienced recurrent DVT while on optimal vitamin K antagonist therapy.
- The patient had no evidence of malignancy or antiphospholipid antibodies.
Findings:
- A new diagnosis of overt hyperthyroidism was established concurrently with the recurrent DVT.
- This association suggests a potential link between hyperthyroidism and DVT recurrence.
Implications:
- Hyperthyroidism should be considered in the differential diagnosis of recurrent DVT, especially in patients with suboptimal risk factors.
- Further research may elucidate the mechanisms linking thyroid dysfunction and hypercoagulability.
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