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Related Concept Videos

Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
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Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...

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Pregnancy Test Use and Timing of Pregnancy Detection in a Prospective Cohort of Pregnancy Planners.

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Letter to the editor: five-year implant versus other contraception missing correct data.

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Venous thromboembolism with combined oral contraceptives based on estrogen and progestin content: a disproportionality analysis of the United States Food and Drug Administration Adverse Event Reporting System database.

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Related Experiment Video

Updated: Jul 10, 2026

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice
08:42

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice

Published on: July 26, 2024

The contraceptive implant.

Heather Hohmann1, Mitchell D Creinin

  • 1Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA. hhohmann@mail.magee.edu

Clinical Obstetrics and Gynecology
|November 6, 2007
PubMed
Summary

The etonogestrel implant offers long-acting, reversible birth control with high effectiveness for three years. While generally safe and beneficial for some conditions, it may cause irregular bleeding.

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Area of Science:

  • Reproductive Health
  • Contraception
  • Endocrinology

Background:

  • Long-acting reversible contraception (LARC) is a key strategy for preventing unintended pregnancies.
  • Subdermal implants offer a discreet and effective LARC option.

Purpose of the Study:

  • To review the characteristics, efficacy, and safety of the etonogestrel contraceptive implant (Implanon).

Main Methods:

  • Review of clinical data and FDA approval information for Implanon.

Main Results:

  • Implanon is a highly effective, 3-year reversible contraceptive implant.
  • It is safe for use during lactation and may improve dysmenorrhea.
  • Potential side effect includes irregular vaginal bleeding; no significant impact on bone density, lipids, or liver enzymes.

Conclusions:

  • The etonogestrel implant is a safe and effective long-acting contraceptive option.
  • It offers benefits beyond contraception, such as improved menstrual symptoms.
  • Healthcare providers should counsel patients on potential bleeding irregularities.