Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

MicroRNAs in vertebrate synapse development.

Roberto Fiore1, Gerhard Schratt

  • 1University of Heidelberg, Interdisciplinary Centre for Neurosciences (IZN), SFB488 Junior Group, and University Hospital of Heidelberg, Institute for Neuroanatomy, Im Neuenheimer Feld 345, 69120 Heidelberg, Germany.

Thescientificworldjournal
|November 6, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcranial pulse stimulation modulates spectral signatures of Alzheimer's disease in the 3×Tg-AD mouse model.

Alzheimer's research & therapy·2026
Same author

Multimodal evaluation of differentiated thyroid cancer patient information booklets: strengths and limitations in content quality, readability, and patient-centered communication.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same author

The Unexplored Role of Noncoding Regulatory RNAs in Engram Dynamics.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry·2026
Same author

Cardiovascular Pre-participation Evaluation of Athletes with an Impairment Recruited for Paris 2024 Paralympic Games.

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension·2025
Same author

Peripheral MicroRNA Expression Patterns as Biomarkers for Adolescent Depression.

Biological psychiatry global open science·2025
Same author

Blood test findings in a large cohort of Olympic athletes: a cross-sectional study.

Journal of science and medicine in sport·2025
Same journal

Opportunities and Challenges of Integrating Ethiopian Traditional Medicine System Into Modern Medicine: A Narrative Review.

TheScientificWorldJournal·2026
Same journal

Exploring the Antiparasitic Activity of the Sea Cucumber Isostichopus sp. aff. badionotus From the Northern Coast of Colombia Against Trypanosoma cruzi.

TheScientificWorldJournal·2026
Same journal

Kalanchoe ceratophylla (Crassulaceae): The True Identity of Sidingin, a Medicinal Plant From Sumatra, Based on Morphological and Molecular Evidence.

TheScientificWorldJournal·2026
Same journal

Genetic Variation of Chicken Growth Differentiation Factor-9 Gene and Association With Egg Characteristics: A Systematic Review.

TheScientificWorldJournal·2026
Same journal

Applied Research on the Effect of Risks on Public Health Building Projects' Performance: Empirical Results From Tanzania.

TheScientificWorldJournal·2026
Same journal

Projected Impacts of Climate and Land Use/Land Cover Change on Sediment Yield and Surface Runoff in the Baro River Sub-Basin, Ethiopia.

TheScientificWorldJournal·2026
See all related articles

MicroRNAs regulate gene expression and are vital for nervous system development, synapse formation, and plasticity. Dysregulation of these small RNAs is implicated in neurological diseases.

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Genetics

Background:

  • MicroRNAs are small noncoding RNAs regulating gene expression post-transcriptionally.
  • They are crucial in vertebrate nervous system development, including neuronal differentiation.
  • Emerging evidence links microRNAs to synaptic plasticity and neurological disorders.

Purpose of the Study:

  • To review the role of microRNAs in synapse formation, plasticity, and disease.
  • To explore microRNA involvement in later stages of neuronal development.
  • To discuss future research on microRNA regulation and cognitive functions.

Main Methods:

  • Literature review of recent studies on microRNAs in neuroscience.
  • Analysis of microRNA function in neuronal development and synaptic processes.

Related Experiment Videos

  • Synthesis of findings related to microRNAs and neurological diseases.

    • Main Results:

    • MicroRNAs are key regulators in neuronal fate determination and differentiation.
    • They play significant roles in the formation and plasticity of synapses.
    • MicroRNAs are implicated in the pathogenesis of diseases involving synaptic dysfunction.

    Conclusions:

    • MicroRNAs are essential for normal neuronal development and synaptic function.
    • Their dysregulation contributes to neurological disease etiology.
    • Further research will elucidate microRNA roles in cognition, learning, and memory.