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[The use of total intravenous anesthesia utilizing klofelin in hypertension patients]
Klinicheskaia Khirurgiia
|January 1, 1991
Insights
Clophelinum administration during anesthesia improved hemodynamic stability in 30 patients with hypertension undergoing surgery. Programmed infusion at 0.75 mcg/(kg·hr) proved most effective for managing blood pressure.
Area of Science:
- Anesthesiology
- Cardiovascular Medicine
- Pharmacology
Context:
- Hypertension management in surgical patients presents unique challenges.
- Total intravenous anesthesia (TIVA) is a common anesthetic technique.
- Hemodynamic instability can complicate surgical procedures, especially in hypertensive patients.
Purpose:
- To evaluate the efficacy of clophelinum in maintaining hemodynamic stability during TIVA.
- To compare different administration methods of clophelinum.
- To determine the optimal dosage and infusion strategy for clophelinum in this patient population.
Summary:
- Clophelinum was administered to 30 patients with stage IIA-IIB hypertension undergoing surgery for various conditions.
- Different clophelinum administration methods were assessed.
- Programmed administration via a "Vita-beta" infusator at 0.75 mcg/(kg·hr) demonstrated optimal hemodynamic stabilization.
Impact:
- This study identifies a precise method for using clophelinum to manage blood pressure during surgery in hypertensive patients.
- Findings can guide anesthesiologists in optimizing anesthetic protocols for improved patient outcomes.
- Establishes a benchmark for clophelinum dosing in TIVA for complex surgical cases.
Abstract:
In 30 patients with IIA-IIB stage hypertension operated on for cholelithiasis, gastric and duodenal ulcer disease and other diseases, clophelinum was used as a component of total intravenous anesthesia. The different methods of its administration were assessed. The optimal variant of hemodynamic stabilization was noted in programmed clophelinum administration by means of infusator "Vita-beta" at a dose of 0.75 g/(kg.hr).