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Related Concept Videos

Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

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Related Experiment Video

Updated: Jul 10, 2026

Integration of Electroporation in Urological Practice: Design and Evaluation of a New Transurethral Electrode
04:45

Integration of Electroporation in Urological Practice: Design and Evaluation of a New Transurethral Electrode

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[Interventional oncology in urology].

J Tacke1

  • 1Institut für Diagnostische und Interventionelle Radiologie/Neuroradiologie, Klinikum Passau, Innstr. 76, 94032, Passau, Deutschland. josef.tacke@klinikum-passau.de

Der Radiologe
|November 6, 2007
PubMed
Summary
This summary is machine-generated.

Early detection of small renal cell carcinomas is increasing. Radiofrequency ablation (RFA) offers a safe and effective treatment option for kidney tumors, with high success rates and low recurrence.

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Area of Science:

  • Urology
  • Oncology
  • Minimally Invasive Surgery

Context:

  • Increasing incidence and improved detection of small renal cell carcinomas.
  • Surgical resection (radical/partial nephrectomy) is the gold standard, often performed laparoscopically.
  • Need for alternative treatments for patients unfit for surgery.

Purpose:

  • To review the efficacy and safety of thermal ablation techniques for renal cell carcinoma.
  • To highlight radiofrequency ablation (RFA) as a primary thermal ablation method.
  • To compare RFA with other treatments and assess its clinical outcomes.

Summary:

  • Radiofrequency ablation (RFA) is effective for renal lesions 2-5 cm in diameter.
  • Percutaneous RFA, guided by imaging, is safe with a low complication rate.
  • Preliminary data suggest RFA may be superior to other thermal ablation techniques, with over 90% clinical success and low local relapse rates.

Impact:

  • RFA provides a viable, minimally invasive treatment for select renal cell carcinoma patients.
  • Offers a safe alternative for patients who cannot undergo or refuse surgical resection.
  • Promising results indicate RFA's potential to become a standard treatment option.