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[Iatrogenic disease in elderly. Case report].

Anca Artenie¹, G Ungureanu

¹Clinica a IV-a Medicină, Spitalul Clinic "Dr. C.I. Parhon" Iaşi.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi

|November 7, 2007

Summary

This summary is machine-generated.

Atherosclerotic renovascular disease, or ARAS, is increasingly common in older adults. Certain medications can pose risks for elderly patients with undiagnosed ARAS, highlighting the need for careful management.

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Area of Science:

Nephrology
Cardiovascular Medicine
Geriatrics

Background:

Increasing life expectancy and medical advances contribute to the rising incidence of ischaemic nephropathy (IN).
Ischaemic nephropathy is characterized by atherosclerotic stenosis in both renal arteries (ARAS).

Observation:

ARAS prevalence increases significantly with cardiovascular comorbidities, reaching 67.5% in peripheral artery atherosclerotic disease.
Patients are often diagnosed late with IN, frequently after dehydration or initiation of ACE inhibitors or ARBs.
Elderly patients with unsuspected ARAS face hazards from ACE inhibitors/ARBs, especially when combined with NSAIDs.

Findings:

The prevalence of ARAS is substantial in elderly individuals with cardiovascular risk factors and escalates with more severe atherosclerotic disease.
Delayed diagnosis of IN is common, often occurring under specific clinical circumstances or medication use.

Implications:

Early recognition of ARAS in at-risk elderly populations is crucial to prevent iatrogenic complications.
Clinicians must exercise caution when prescribing ACE inhibitors, ARBs, and NSAIDs to elderly patients due to potential risks associated with undiagnosed ARAS.
Managing comorbidities and polypharmacy in the elderly is essential for mitigating the risk of iatrogenic IN.