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Updated: Jul 10, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
Postoperative perforation in the bronchus intermedius membrane after a primary lung cancer resection
Yuji Hirami1, Shinichi Toyooka, Yoshifumi Sano
1Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry, and Pharmaceutical Science, Okayama University, 2-5-1 Shikata-cho, Okayama city, Okayama 700-8558, Japan. yhirami@med.kawasaki-m.ac.jp
Abstract:
We experienced 4 cases of postoperative perforation in the bronchus intermedius membrane (PBIM) after primary lung cancer resection. Three patients had undergone a right lower lobectomy and 1 patient had undergone a right upper lobectomy; as part of a systemic lymph node dissection, the subcarinal lymph node (Station 7) was dissected in all cases. Leakages were detected on postoperative days 3, 10, 11, and 26, respectively. The clinical signs of PBIM included the appearance of sputum like pleural effusion, decreased oxygenation, elevated inflammatory markers, pneumothorax, and infected pleural effusion. PBIM was confirmed by bronchofiberscopy. Direct suturing of the perforated membrane, followed by rapping with an omental flap was performed in 1 case; completion bilobectomies, followed by rapping of the bronchial stump with an omental flap or an intercostal muscle flap were performed in 2 cases; and a completion pneumonectomy, followed by rapping of the bronchial stump with an omental flap was performed in 1 case. All 4 of the cases were successfully treated.
Insights
Postoperative perforation in the bronchus intermedius membrane (PBIM) is a rare complication after lung cancer surgery. Prompt diagnosis and surgical intervention led to successful treatment in all four reported cases.
Area of Science:
- Thoracic Surgery
- Surgical Complications
- Pulmonology
Background:
- Primary lung cancer resection involves complex surgical procedures.
- Systemic lymph node dissection, including subcarinal nodes (Station 7), is a critical component.
- Rare complications like bronchus intermedius membrane perforation can occur post-surgery.
Observation:
- Four cases of postoperative perforation in the bronchus intermedius membrane (PBIM) were identified after lung cancer resection.
- Clinical signs included sputum-like pleural effusion, hypoxia, inflammation, pneumothorax, and infected effusion.
- Diagnosis was confirmed via bronchofiberscopy.
Findings:
- Surgical interventions included direct suturing with omental flap, completion bilobectomies, or completion pneumonectomy.
- All surgical repairs were augmented with omental or intercostal muscle flaps.
- All four patients were successfully treated with the implemented surgical strategies.
Implications:
- PBIM is a significant postoperative complication requiring timely recognition and management.
- Various surgical techniques can effectively manage PBIM, ensuring positive patient outcomes.
- This case series highlights successful treatment modalities for PBIM after lung cancer surgery.
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