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Published on: August 15, 2019
The HGNC Database in 2008: a resource for the human genome
Elspeth A Bruford1, Michael J Lush, Mathew W Wright
1European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, UK.
Nucleic Acids Research
|November 7, 2007
Summary
The HUGO Gene Nomenclature Committee (HGNC) provides unique names and symbols for human genes. Their updated database at genenames.org offers comprehensive gene information and related bioinformatics tools.
Area of Science:
- Genetics
- Bioinformatics
- Human Genomics
Background:
- The HUGO Gene Nomenclature Committee (HGNC) is responsible for assigning standardized names and symbols to human genes.
- Accurate gene nomenclature is crucial for clear communication and data integration in genetics research.
Purpose of the Study:
- To provide an updated overview of the HGNC resource and its functionalities.
- To highlight the HGNC database's expansion and accessibility.
Main Methods:
- The HGNC curates and maintains a comprehensive database of human gene nomenclature.
- The database is publicly accessible via a dedicated homepage with search functionalities.
Main Results:
- The HGNC database contains over 24,000 approved human gene records.
- The HGNC resource is now hosted at the European Bioinformatics Institute (EMBL-EBI).
- Direct links to related resources like the HCOP orthology tool and gene family pages are provided.
Conclusions:
- The HGNC continues to be a vital resource for human gene identification and information.
- The new web presence enhances accessibility to gene nomenclature data and associated tools.
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