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Related Experiment Video

Updated: Jul 10, 2026

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

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Published on: July 15, 2021

Introduction: array technology - an overview.

Hartmut Seliger¹

¹Arbeitsgruppe Chemische Funktionen in Biosystemen, Universitat Ulm, Ulm, Germany.

Methods in Molecular Biology (Clifton, N.J.)

|November 7, 2007

Summary

Microarray technology enables high-throughput screening of biomacromolecules for applications in genomics and proteomics. This technology provides new insights into cellular processes and disease development.

Area of Science:

Biotechnology
Molecular Biology
Genomics

Background:

Microarray technology originates from high-throughput parallel synthesis and combinatorial science.
Arrays can be prepared via in situ or ex situ synthesis of biomacromolecules on solid substrates.

Purpose of the Study:

To explore the applications of microarray technology in various scientific fields.
To highlight the utility of microarrays in understanding cellular processes and disease.

Main Methods:

Utilizes high-throughput parallel synthesis and combinatorial approaches for biomacromolecule preparation.
Employs spatial addressing for target molecules and screening of interactions between immobilized probes and targets.
Focuses on nucleic acid arrays due to their straightforward hybridization screening capabilities.

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Technical Demonstration of Whole Genome Array Comparative Genomic Hybridization

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Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays for High-Throughput Large-Scale Sample Inspection

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Last Updated: Jul 10, 2026

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

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Published on: June 13, 2023

Main Results:

Nucleic acid arrays are well-developed, enabling the study of the biosynthetic pathway from genes to proteins.
Microarray applications are prominent in genomics, transcriptomics, proteomics, and glycomics.
Facilitates new insights into the molecular basis of cellular processes and disease development.

Conclusions:

Microarray technology is a powerful tool for large-scale screening and analysis.
Its applications are crucial for advancing our understanding in the postgenomic era.
Enables significant progress in deciphering complex biological systems and diseases.