Jove
Visualize
Contact Us

Related Experiment Videos

Primers on chromatin.

Sabbi Lall1

  • 1s.lall@natureny.com

Nature Structural & Molecular Biology
|November 7, 2007
PubMed
Summary
This summary is machine-generated.

This resource simplifies complex chromatin research, covering histone modifications, enzymes, recognition modules, and remodeling complexes. It provides foundational knowledge for understanding gene regulation and chromatin structure.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A bottle opener for TBP.

Nature structural & molecular biology·2011
Same author

Channeling sperm activation.

Nature structural & molecular biology·2010
Same author

Silence of the budding yeast.

Nature structural & molecular biology·2009
Same author

Activating apoptosis.

Nature structural & molecular biology·2009
Same author

Sinister symphony in e1a.

Nature structural & molecular biology·2008
Same author

No SIRT6.

Nature structural & molecular biology·2008
Same journal

Genome-wide absolute quantification of chromatin looping.

Nature structural & molecular biology·2026
Same journal

Putting numbers on chromatin looping.

Nature structural & molecular biology·2026
Same journal

Transcriptional readthrough progresses from incidental byproduct to therapeutic opportunity.

Nature structural & molecular biology·2026
Same journal

Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity.

Nature structural & molecular biology·2026
Same journal

Structurally defining neurokinin selectivity to improve NK2R agonists.

Nature structural & molecular biology·2026
Same journal

Surveying the roles of NINJ1 in plasma membrane rupture.

Nature structural & molecular biology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Molecular Biology
  • Genetics
  • Biochemistry

Background:

  • Chromatin structure is crucial for gene regulation.
  • Histone modifications play key roles in cellular processes.
  • Understanding chromatin dynamics requires knowledge of its components and their interactions.

Purpose of the Study:

  • To provide a simplified overview of key areas in chromatin research.
  • To serve as a foundational resource for scientists entering the field.
  • To highlight the complexity and context-dependency of chromatin modifications.

Main Methods:

  • Compilation of knowledge in four key areas of chromatin research.
  • Inclusion of representative structural information with references.
  • Provision of online resources with hyperlinks to structural databases.

Related Experiment Videos

Main Results:

  • A comprehensive primer series covering covalent histone modifications, modifying enzymes, chromatin recognition modules, and ATP-dependent chromatin remodeling complexes.
  • Illustrative examples of context-dependent modifications, such as H3K9 methylation.
  • Accessible structural data through hyperlinks and 3D viewing capabilities.

Conclusions:

  • The provided primers offer a simplified yet informative entry point into chromatin research.
  • The resource emphasizes the context-dependent nature of histone modifications and their functions.
  • The primers are designed as a dynamic, adaptable tool for ongoing scientific learning.