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Updated: Jul 10, 2026

Ex Vivo Corneal Organ Culture Model for Wound Healing Studies
Published on: February 15, 2019
Shewanella putrefaciens keratitis in the lamellar bed 6 years after LASIK
Hee-Jung S Park1, Sonal S Tuli, Donald M Downer
1Department of Ophthalmology, University of Florida, Gainesville, Fla, USA.
Purpose:
To present a case of infectious keratitis occurring 6 years after LASIK due to the rare human pathogen Shewanella putrefaciens.
Methods:
A 58-year-old man presented with redness and pain in the right eye 6 years following LASIK retreatment. Examination revealed a corneal infiltrate at the flap interface. Corneal scraping of stroma beneath the flap was submitted for histopathologic and microbiologic evaluation.
Results:
An infiltrate located at the LASIK flap interface originated from an epithelial defect at the flap-corneal junction. Corneal stroma cultures demonstrated Shewanella putrefaciens. The infection resolved with antibiotic treatment.
Conclusions:
LASIK-related complications, such as infections, can occur many years following the procedure. The potential space created under the LASIK flap may predispose patients to infection by opportunistic organisms.

