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Related Experiment Video

Updated: Jul 10, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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The alcohol withdrawal syndrome.

A McKeon1, M A Frye, Norman Delanty

  • 1Department of Neurology and Clinical Neurosciences, Beaumont Hospital, Dublin, and Royal College of Surgeons in Ireland, Dublin, Ireland. mckeon.andrew@mayo.edu

Journal of Neurology, Neurosurgery, and Psychiatry
|November 8, 2007
PubMed
Summary

Alcohol withdrawal syndrome (AWS) requires careful management, with severe cases needing inpatient care and benzodiazepines. A multidisciplinary approach ensures safe detoxification for most patients experiencing AWS.

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Area of Science:

  • Neurology
  • Psychiatry
  • General Medicine

Background:

  • Alcohol withdrawal syndrome (AWS) is a frequent challenge in hospital settings.
  • Management varies from outpatient to intensive inpatient care based on symptom severity and patient history.
  • AWS often co-occurs with complex issues like delirium tremens, Wernicke-Korsakoff syndrome, seizures, and liver disease.

Purpose of the Study:

  • To outline the common management problems associated with alcohol withdrawal syndrome.
  • To emphasize the need for a coordinated, multidisciplinary approach in managing AWS.
  • To highlight that safe detoxification is achievable for most patients with careful evaluation and treatment.

Main Methods:

  • Review of common clinical presentations and complications of AWS.
  • Discussion of treatment strategies, including benzodiazepine therapy for severe cases.
  • Emphasis on the importance of a multidisciplinary team approach.

Main Results:

  • AWS presents a spectrum of severity, necessitating tailored management plans.
  • Co-occurring conditions significantly complicate AWS treatment.
  • Effective management hinges on comprehensive evaluation and appropriate interventions.

Conclusions:

  • Alcohol withdrawal syndrome is a common yet complex condition requiring specialized medical attention.
  • A coordinated, multidisciplinary strategy is crucial for managing the multifaceted aspects of AWS.
  • With careful assessment and available treatments, safe detoxification is attainable for the majority of affected individuals.