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Related Concept Videos

Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

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Related Experiment Video

Updated: Jul 10, 2026

Isolating Stem Cells from Soft Musculoskeletal Tissues
07:49

Isolating Stem Cells from Soft Musculoskeletal Tissues

Published on: July 5, 2010

Stem cells.

Carlo Alberto Redi1, Manuela Monti, Valeria Merico

  • 1Direzione Scientifica Fondazione IRCCS Policlinico San Matteo, Italy.

Endocrine Development
|November 8, 2007
PubMed
Summary

Stem cell research offers new hope for treating diseases like diabetes and Parkinson's through cell replacement. Understanding cell reprogramming could lead to generating tissues and organs for regenerative medicine.

Area of Science:

  • Biomedicine
  • Regenerative Medicine
  • Stem Cell Biology

Background:

  • Stem cells are crucial for treating various diseases, with successful applications in heart disease, diabetes, Parkinson's, severe burns, and blood tumors.
  • Current research addresses fundamental questions in stem cell biology, particularly the mechanisms driving cell proliferation and differentiation.

Purpose of the Study:

  • To explore the potential of stem cells in regenerative medicine.
  • To understand the molecular mechanisms of cell differentiation and dedifferentiation through genome reprogramming.
  • To outline the role of stem cells in normal development and disease treatment.

Main Methods:

  • Overview of stem cell biology and their roles in development.
  • Discussion of genome reprogramming techniques, including nuclear transfer and cytoplast action.

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Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation
09:57

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation

Published on: December 21, 2016

Related Experiment Videos

Last Updated: Jul 10, 2026

Isolating Stem Cells from Soft Musculoskeletal Tissues
07:49

Isolating Stem Cells from Soft Musculoskeletal Tissues

Published on: July 5, 2010

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation
09:57

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation

Published on: December 21, 2016

  • Review of current and potential applications in cell replacement therapies.
  • Main Results:

    • Stem cell applications have shown success in treating conditions such as infarcted heart, diabetes, and Parkinson's disease.
    • Genome reprogramming is expected to elucidate molecular pathways of cell differentiation and dedifferentiation.
    • Potential for generating cell populations for tissue and organ development.

    Conclusions:

    • Stem cells hold significant promise for treating a wide range of diseases.
    • Further research into stem cell mechanisms, especially reprogramming, is vital for advancing regenerative medicine.
    • The development of therapies using stem cells could revolutionize patient care for numerous conditions.