Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Multiple Allele Traits

Multiple Allele Traits

The Concept of Multiple Allelism

Multiple Allele Traits

Multiple Allele Traits

The Concept of Multiple Allelism

Monohybrid Crosses

Monohybrid Crosses

Monohybrid Crosses

Monohybrid Crosses

Polygenic Traits

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...

Polygenic Traits

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Experimental Limits on Solar Reflected Dark Matter with a New Approach on Accelerated-Dark-Matter-Electron Analysis in Semiconductors.

Physical review letters·2024

Same author

Constraints on Sub-GeV Dark Matter-Electron Scattering from the CDEX-10 Experiment.

Physical review letters·2022

Same author

Exotic Dark Matter Search with the CDEX-10 Experiment at China's Jinping Underground Laboratory.

Physical review letters·2022

Same author

[A protein complex recognition method based on spatial-temporal graph convolution neural network].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2022

Same author

A systematic review and meta-analysis on the efficacy of probiotics for bacterial vaginosis.

European review for medical and pharmacological sciences·2022

Same author

[Role and implementation experience of splints in pediatric burn rehabilitation].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns·2020

Search research articles

Related Experiment Video

Updated: Jul 10, 2026

Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization

Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

Advances in Bayesian multiple quantitative trait loci mapping in experimental crosses.

N Yi¹, D Shriner

¹Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294-0022, USA. nyi@ms.soph.uab.edu

|November 8, 2007

Summary

Bayesian methods offer advanced tools for mapping multiple quantitative trait loci (QTL) in complex genetic studies. This review highlights recent Bayesian approaches for QTL mapping and their applications in understanding disease genetics.

More Related Videos

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

Related Experiment Videos

Last Updated: Jul 10, 2026

Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization

Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

Area of Science:

Genetics
Bioinformatics
Statistical Genetics

Background:

Complex human diseases and traits are influenced by multiple interacting quantitative trait loci (QTL) and environmental factors.
Mapping QTL is essential for understanding the genetic basis of complex traits and identifying responsible genes.

Purpose of the Study:

To review recently developed and emerging Bayesian methods for multiple QTL mapping in experimental crosses.
To compare and contrast different Bayesian approaches and associated software.
To identify future research directions in Bayesian QTL mapping.

Main Methods:

Review of advanced statistical methods, focusing on Bayesian approaches for multiple QTL mapping.
Comparative analysis of various Bayesian methods and their computational software.
Discussion of the joint inference capabilities of Bayesian methods for QTL number, position, and effects.

Main Results:

Bayesian methods have significantly advanced the field of multiple QTL mapping over the past decade.
These methods enable joint inference of QTL number, genomic positions, and genetic effects.
A range of recently developed Bayesian methods and software are available for experimental crosses.

Conclusions:

Bayesian approaches represent a remarkable evolution in multiple QTL mapping.
Further research is needed to refine and expand upon existing Bayesian methods.
Continued development of Bayesian software will enhance the study of complex genetic traits.