Related Experiment Video
Updated: Jul 10, 2026

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
Published on: September 22, 2023
Postpartum mothers' attitudes, knowledge, and trust regarding vaccination
Ann Chen Wu1, Daryl J Wisler-Sher, Katherine Griswold
1Department of Ambulatory Care and Prevention, Harvard Medical School, and Children's Hospital, 133 Brookline Avenue, 6th Floor, Boston, MA 02215-5301, USA. ann.wu@childrens.harvard.edu
Postpartum mothers express concerns about infant vaccinations, with many desiring more information during pregnancy. Primiparous mothers, low-income mothers not on WIC, and breastfeeding mothers may require targeted vaccine trust-building efforts.
Area of Science:
- Maternal and Child Health
- Vaccinology
- Public Health
Background:
- Postpartum mothers' attitudes and knowledge regarding infant vaccinations are crucial for public health.
- Understanding maternal concerns is key to improving vaccination rates and addressing vaccine hesitancy.
Purpose of the Study:
- To examine postpartum mothers' attitudes and knowledge concerning infant vaccinations.
- To identify factors associated with vaccine mistrust in this population.
Main Methods:
- A cross-sectional study surveyed 228 postpartum mothers at a large teaching hospital in Connecticut.
- Multivariable analysis was employed to identify mothers with lower trust in vaccines.
Main Results:
- 29% of mothers worried about infant vaccinations, citing concerns about efficacy and administration.
- Poor knowledge about vaccines was observed; only 33% correctly linked chickenpox to the varicella vaccine.
- Mothers planning to breastfeed, primiparous mothers, and low-income mothers not receiving WIC support showed less vaccine trust.
Conclusions:
- Despite high vaccination rates, maternal concerns and a desire for earlier immunization information (during pregnancy) are evident.
- Primiparous, low-income (non-WIC), and breastfeeding mothers may need tailored approaches to build vaccine trust.
- Enhanced prenatal education on vaccine risks and benefits is recommended to improve maternal knowledge and confidence.
Related Concept Videos
Vaccinations
Development of the Oral Microbiota
Development of Human Microbiota
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Vaccines
Relationship with Parents: Attachment
