Related Experiment Video
Updated: Jul 10, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
[Invasive pulmonary aspergillosis--imaging and invasive potential of diagnosis]
1Department of Internal Medicine and Hematooncology, 1st Medical Faculty, Charles University Prague, Czech Republic. janhaber@quick.cz
Abstract:
The increasing incidence of invasive pulmonary aspergillosis (IPA), especially in haemato-oncological patients, has led to recent extension and refinement of diagnostic procedures, in particular imaging examinations. From a diagnostic point of view, chest radiography is not beneficial in most IPA cases. Today, the highest diagnostic value is achieved by CT, with an apparent correlation between CT scans and pathological-anatomical findings. A usual CT finding seen in bronchoinvasive aspergillosis is a tree-in-bud pattern. Angioinvasive aspergillosis is typically characterized by initial condensation surrounded by a halo sign--an area of opacity--and, later, by an air-crescent sign--a cavitating lesion. Although the morphology of CT findings is not entirely specific, together with the clinical condition and other assessment methods, these are essential for diagnosis. In rare cases, CT angiography is indicated to clarify the CT findings. If the diagnosis still remains unclear, biopsy examination should be considered, bearing in mind possible complications.
Related Concept Videos
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Pneumonia III: Complications and Assessment
Cryptococcal Meningitis
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
