Analysis of alkamides and caffeic acid derivatives from Echinacea simulata and E. paradoxa roots

The constituents of the roots of Echinacea simulata and E. paradoxa were examined by HPLC. The major lipophilic and hydrophilic compounds could be identified. E. paradoxa contained several ketoalkenynes and proved to have almost identical constituents as E. pallida. E. simulata contained alkamides as found in E. angustifolia and in addition ketoalkenynes as in E. pallida. Echinacoside was found in both species.