Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Mats01:25

Microbial Mats

Microbial communities forming biofilms and mats represent complex, spatially structured ecosystems where metabolic processes are stratified according to light, oxygen, and nutrient gradients. Biofilms are initial colonization stages, only a few millimeters thick, while mature microbial mats can reach centimeter-scale thickness and display intricate vertical organization. Their structural and functional heterogeneity allows microorganisms to occupy distinct ecological niches within a few...
Hyperthermophilic Bacteria01:21

Hyperthermophilic Bacteria

Domain Bacteria includes some unique hyperthermophilic species. They exhibit remarkable adaptations that enable survival in extreme environments.Thermotoga species are rod-shaped, gram-negative, non-sporulating hyperthermophiles that form a sheath-like envelope called a toga. They ferment sugars or starch, producing lactate, acetate, CO₂, and H₂, and can also grow via anaerobic respiration using H₂ and ferric iron. Found in hot springs and hydrothermal vents, over 20% of their genes show strong...
Archaeal Cell Wall01:29

Archaeal Cell Wall

Archaeal cell walls are structurally and compositionally distinct from their bacterial counterparts, lacking the characteristic peptidoglycan layer found in most bacteria. Instead, archaeal cell walls exhibit remarkable diversity, utilizing materials such as pseudomurein, polysaccharides, and proteins to construct their protective outer layers. This structural flexibility is closely tied to archaea's ecological adaptability.S-Layers: The Common Archaeal Cell WallThe S-layer is the most...
Bacterial Phylum Planctomycetes01:26

Bacterial Phylum Planctomycetes

Planctomycetes are a group of morphologically distinct bacteria predominantly classified into two orders: Planctomycetales and Brocadiales. These gram-negative bacteria exhibit unique features, including division by budding and the presence of stalks or appendages. Their cells are often found in rosette arrangements, and they are notable for possessing an S-layer in their cell envelope, which is relatively uncommon among bacteria. Additionally, Planctomycetes frequently exhibit intracellular...
Anoxygenic Phototrophic Bacteria01:28

Anoxygenic Phototrophic Bacteria

Anoxygenic phototrophic bacteria are a diverse group of microorganisms that perform photosynthesis without producing oxygen. They primarily include purple sulfur bacteria, purple nonsulfur bacteria, green sulfur bacteria, and green nonsulfur bacteria. These bacteria are classified into the Gammaproteobacteria, Alphaproteobacteria, Betaproteobacteria, Chlorobi, and Chloroflexi lineages, each with distinct physiological and ecological adaptations.Purple sulfur bacteria belong to the...
Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Membrane Vesicle-Mediated Delivery of Antibacterial Lipopeptides by <i>Pseudoalteromonas piscicida</i>.

ACS chemical biology·2026
Same author

Lipopeptides and antibiotics from a marine <i>Bacillus pumilus</i> mediate a potential "catch and kill" effect on pathogenetic <i>Vibrio parahaemolyticus</i>.

mSystems·2025
Same author

Vicariance and cryptic diversity revealed by molecular phylogenetic analyses of estuarine Gammarus species (Crustacea: Amphipoda) due to formation of the Labrador Current.

Invertebrate systematics·2025
Same author

Specialization of Sesquiterpene Lactone Metabolites in <i>Liriodendron</i> Plant Defense.

Journal of natural products·2025
Same author

Mycoremediation of Louisiana sweet crude oil with Pleurotus ostreatus and nutrient amendments.

Environmental toxicology and chemistry·2025
Same author

Metabolic flux regulates growth transitions and antibiotic tolerance in uropathogenic <i>Escherichia coli</i>.

Journal of bacteriology·2024

Related Experiment Video

Updated: Jul 10, 2026

Adaptation at the Extremes of Life: Experimental Evolution with the Extremophile Archaeon Sulfolobus acidocaldarius
08:11

Adaptation at the Extremes of Life: Experimental Evolution with the Extremophile Archaeon Sulfolobus acidocaldarius

Published on: June 14, 2024

Bacillamides from a hypersaline microbial mat bacterium.

Aaron M Socha1, Richard A Long, David C Rowley

  • 1Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, USA.

Journal of Natural Products
|November 9, 2007
PubMed
Summary
This summary is machine-generated.

Researchers discovered two new tryptamide thiazole metabolites, bacillamides B and C, from the bacterium Bacillus endophyticus found in a Bahamian hypersaline environment. These compounds were identified using advanced spectroscopic and chromatographic methods.

More Related Videos

Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution
07:20

Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution

Published on: December 30, 2021

Extraction of High Molecular Weight DNA from Microbial Mats
09:30

Extraction of High Molecular Weight DNA from Microbial Mats

Published on: July 7, 2011

Related Experiment Videos

Last Updated: Jul 10, 2026

Adaptation at the Extremes of Life: Experimental Evolution with the Extremophile Archaeon Sulfolobus acidocaldarius
08:11

Adaptation at the Extremes of Life: Experimental Evolution with the Extremophile Archaeon Sulfolobus acidocaldarius

Published on: June 14, 2024

Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution
07:20

Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution

Published on: December 30, 2021

Extraction of High Molecular Weight DNA from Microbial Mats
09:30

Extraction of High Molecular Weight DNA from Microbial Mats

Published on: July 7, 2011

Area of Science:

  • Marine microbiology
  • Natural product chemistry
  • Metabolomics

Background:

  • Hypersaline environments harbor unique microbial communities with potential for novel metabolite discovery.
  • Bacillus endophyticus is a bacterium known to inhabit diverse ecological niches.
  • Tryptamide thiazole metabolites represent a class of natural products with diverse biological activities.

Purpose of the Study:

  • To isolate and characterize novel secondary metabolites from Bacillus endophyticus.
  • To investigate the chemical diversity of microorganisms from Bahamian hypersaline microbial mats.
  • To elucidate the structures of newly discovered compounds.

Main Methods:

  • Isolation of Bacillus endophyticus from a Bahamian hypersaline microbial mat.
  • Cultivation and fermentation of the bacterial isolate.
  • Bioassay-guided fractionation using High-Performance Liquid Chromatography-Ultraviolet-Mass Spectrometry (HPLC-UV-MS).
  • Structure elucidation using combined spectroscopic techniques (e.g., NMR, MS).

Main Results:

  • Two new tryptamide thiazole metabolites, designated bacillamides B and C, were isolated.
  • The structures of bacillamides B and C were fully elucidated.
  • The compounds were identified as trace fermentation products.

Conclusions:

  • Bacillus endophyticus from hypersaline environments produces novel tryptamide thiazole metabolites.
  • Advanced analytical techniques are crucial for detecting and characterizing trace natural products.
  • The discovery of bacillamides B and C expands the known repertoire of microbial secondary metabolites.