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Updated: Jul 10, 2026
Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus
Published on: March 28, 2025
[Immunolocalization of the antioxidant protein TPx of Echinococcus granulosus]
Qiu-Lian Hou1, Hui Wang, Zhuang-Zhi Zhang
1Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.
Aim:
To study the localization of the antioxidant protein thioredoxin peroxidase (TPx) of Echinococcus granulosus (EgTPx) in the protoscoleces (PSC) of parasite.
Methods:
The protoscoleces of E.granulosus were aspirated and pooled from sheep liver hydatid cysts. After digested by pepsin, the sedimented protoscoleces were used for paraffin sections. The localization of the antioxidant protein TPx of EgTPx was determined by using(polyclonal antibody against rEgTPx) and indirect immunofluorescence staining.
Results:
Indirect immunofluorescence staining analysis indicated that the rEgTPx was mainly distributed in tegument, subtegument and calcareous corpuscle cells of the protoscolex.
Conclusion:
The wide distribution and large sites of EgTPx in the parasite hare been clearly determined, which will help further investigation into the biological functions and application of TPx protein.
