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Is there an association between left bundle branch block and coronary slow flow in patients with normal coronary
Serdar Biceroglu1, Ahmet Yildiz, Serdar Bayata
1Izmir Gazi Hospital, Izmir, Turkey. sserdarbicer@gmail.com
Insights
Coronary slow flow in normal arteries is linked to conduction disorders. This study found a strong association, particularly with left bundle branch block, suggesting further research into a causal relationship.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Slow flow in coronary arteries with normal angiography is a recognized clinical issue.
- The relationship between coronary slow flow and cardiac conduction disorders remains unclear.
- Microvascular dysfunction is a proposed cause for coronary slow flow.
Purpose of the Study:
- To investigate the frequency of conduction disorders in patients presenting with coronary slow flow and angiographically normal coronary arteries.
- To determine if there is an association between left bundle branch block (LBBB) or right bundle branch block (RBBB) and coronary slow flow.
Main Methods:
- Analysis of 12-lead electrocardiograms (ECG) in 36 patients diagnosed with coronary slow flow.
- Assessment for the presence of bundle branch blocks (BBB) and intraventricular conduction delays.
- Coronary angiography was used to confirm normal coronary arteries and diagnose slow flow.
Main Results:
- Left bundle branch block (LBBB) was identified in 61% of patients (22 out of 36).
- Normal intraventricular conduction was observed in 33% of patients (12 out of 36).
- Right bundle branch block (RBBB) was present in only 6% of patients (2 out of 36).
Conclusions:
- A significant association exists between coronary slow flow and conduction abnormalities, especially LBBB.
- The findings suggest a potential link beyond microvascular disease, warranting further investigation into causality.
- Future studies should explore a direct causal relationship between LBBB and coronary slow flow.
Abstract:
Slow flow in angiographically normal coronary arteries is not a rarely seen problem. It is unknown whether it is related with conduction disorders. In this study we investigated the frequency of conduction disorders in patients with normal coronary artery and slow flow. The study included 36 (22 female; mean age 63 +/-11 years) patients who have normal coronary arteries and slow flow in coronary angiography. Patients' 12-lead electrocardiograms were analyzed for the presence of bundle branch block. Twenty-two of 36 patients (61%) demonstrated left bundle branch block. Twelve patients (33%) had normal intraventricular conduction. Only 2 of 36 patients (6%) had right bundle branch block. Microvascular disease has been implicated in coronary slow flow. However, according to the results of this study there is a close association between especially left bundle branch block and coronary slow flow. A causal relation should be sought between them with future studies.
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