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Nephrogenic fibrosing dermopathy: report of two cases
Nádia Barbosa Aires1, Mírian N Sotto, Marcello M S Nico
1Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil. nadiaaires@yahoo.com.br
Abstract:
Nephrogenic fibrosing dermopathy is a recently described fibrosing disorder that emerges in different settings of renal insufficiency. The degree and cause of the underlying renal impairment seem not to be related to the severity of the nephrogenic fibrosing dermopathy. Lesions are typically symmetrical and usually develop on the limbs and trunk. These are characterized by skin-coloured to erythematous papules that coalesce into plaques markedly thickened in texture. Flexion contractures of the joints may be a feature of the disease. There is no consistently effective therapy for nephrogenic fibrosing dermopathy. We report here 2 Brazilian patients in connection with a short review. Remission was recorded in one case after plasmapheresis.
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