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Strokes after cardiac surgery: mostly right hemispheric ischemic with mild residual damage
I Korn-Lubetzki1, A Oren, E Asher
1Dept. of Neurology, Shaare Zedek Medical Center, 3235, Jerusalem, 91031, Israel. ikl@md.huji.ac.il
Insights
Cardiac surgery patients experiencing stroke or transient ischemic attack (TIA) predominantly suffer right-hemispheric, ischemic events. Most patients achieve functional independence, suggesting a procedure-related embolic mechanism.
Area of Science:
- Neurology
- Cardiology
- Vascular Surgery
Background:
- Cardiac surgery is increasingly performed on high-risk patients with pre-existing cerebrovascular disease.
- Acute stroke and transient ischemic attack (TIA) are potential complications following cardiac procedures.
Purpose of the Study:
- To investigate the clinical findings and medium-term outcomes of patients who experience acute stroke or TIA after cardiac surgery.
- To identify risk factors, stroke characteristics, and neurological deficits in this patient population.
Main Methods:
- Prospective observation of consecutive patients undergoing cardiac surgery over a 19-month period.
- Detailed evaluation of risk factors, stroke type, localization, initial deficit, and follow-up outcomes using standard assessment scores.
- Follow-up duration ranged from 3 to 21 months.
Main Results:
- Eighteen patients developed stroke and 2 experienced TIAs among 406 operated patients.
- Most strokes were right-hemispheric and ischemic, occurring shortly after valve surgery.
- Vertebrobasilar strokes appeared later and were linked to cardiac arrhythmias; two such cases resulted in in-hospital mortality.
- Stroke/TIA patients had worse cardiac functional scores and longer cardiopulmonary bypass times, but not higher preoperative risk.
Conclusions:
- Strokes following cardiac surgery are predominantly right-hemispheric and ischemic.
- The overall outcome for hemispheric stroke patients is relatively favorable, with most achieving functional independence.
- A procedure-related embolic injury to the right hemisphere is proposed as a likely mechanism.
Objective:
Since cardiac surgery is now performed on patients with high risk for cerebrovascular disease, we studied the clinical findings and medium term outcome of patients with acute stroke/transient ischemic attack (TIA) after cardiac surgery.
Methods:
All consecutive patients with acute stroke/TIA after cardiac surgery were prospectively observed during a 19 month period. Follow-up was between 3 months and 21 months. Risk factors, type of stroke, anatomic localization, initial neurological deficit and followup outcome were evaluated, using standard assessment scores.
Results:
Among 406 patients operated (mean age 64.3 +/- 12.7 years, 284 males), 18 developed stroke and 2 TIAs (mean age 65.7 years, 13 males). There were no cases of intracerebral hemorrhage. Most of the strokes happened shortly after valve surgery (mean 1.3 days post operatively) and were right hemispheric (right = 11, left = 3; p = 0.034). Vertebrobasilar stroke appearance was delayed (mean: 8.25 days post operatively); they were attributed mostly to cardiac arrhythmias. Stroke/TIA patients did not have a higher preoperative risk than those without, but their cardiac functional score was worse (p = 0.01), and the average cardiopulmonary bypass time during surgery was longer (p = 0.009). Two patients died in hospital, both with vertebrobasilar stroke. Most of the hemispheric stroke patients became functionally independent (mean modified Rankin Scale < 2), even those with initial severe deficit.
Conclusion:
Strokes after cardiac surgery are mostly right hemispheric and exclusively ischemic. Outcome is relatively fair. We suggest an embolic injury to the right hemisphere, procedure related, as a possible mechanism.
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