Related Experiment Video
Updated: Jan 3, 2026

Cigarette Smoke Exposure in Mice using a Whole-Body Inhalation System
Published on: October 22, 2020
Association between environmental tobacco smoke exposure and wheezing disorders in Austrian preschool children
Elisabeth Horak1, Bernhard Morass, Hanno Ulmer
1Department of Pediatrics and Adolescents, Division of Pediatric Cardiology and Pulmonology, Innsbruck Medical University, Innsbruck, Austria. Elisabeth.Horak@uki.at
Insights
Prenatal exposure to environmental tobacco smoke (ETS) significantly increases the risk of wheezing and asthma in preschool children. Children exposed to ETS also have poorer nutrition, including less breastfeeding and lower fruit/vegetable intake.
Area of Science:
- Pediatric Environmental Health
- Respiratory Medicine
- Allergy and Immunology
Background:
- Passive smoking, or environmental tobacco smoke (ETS) exposure, poses significant health risks, particularly to vulnerable populations like fetuses and young children.
- Previous research indicates a strong impact of ETS on early life development, necessitating further investigation into specific disorders.
- Atopic and wheezing disorders are common in childhood and may be influenced by environmental factors such as ETS.
Purpose of the Study:
- To investigate the effect of environmental tobacco smoke (ETS) exposure on atopic and wheezing disorders in Austrian preschool children.
- To assess the association between prenatal ETS exposure and the development of wheezing and asthma.
- To explore the relationship between ETS exposure and lifestyle factors like breastfeeding and diet in preschool children.
Main Methods:
- A cross-sectional questionnaire survey was conducted among 1737 Austrian preschool children.
- Data collected included information on passive smoking exposure (ETS) and the prevalence of wheezy bronchitis, asthma, hay fever, and atopic dermatitis.
- Statistical analysis was performed to determine the odds ratios (OR) and confidence intervals (CI) for the association between ETS exposure and health outcomes.
Main Results:
- Up to 46% of children were exposed to ETS, with higher risk observed in those from lower socioeconomic backgrounds.
- Prenatal ETS exposure was significantly linked to an increased risk of wheezing in the first year of life (OR 1.6) and past 12 months (OR 1.5).
- Doctor-diagnosed asthma risk was significantly higher in children with prenatal ETS exposure (OR 2.1), and smoking families reported less breastfeeding and lower fruit/vegetable consumption.
Conclusions:
- Prenatal environmental tobacco smoke (ETS) exposure is a confirmed risk factor for wheezing and asthma in preschool children.
- Children exposed to ETS exhibit less healthy lifestyle patterns, including reduced breastfeeding and lower intake of fruits and vegetables.
- The combination of ETS exposure and poor nutrition raises concerns about increased oxidative stress and long-term health in affected children.
Questions:
Passive smoking is a problem in children and adults, but recent studies found the impact to be strongest in the developing foetus and the first years of life. In this cross sectional study we investigated the effect of environmental tobacco smoke (ETS) on atopic and wheezing disorders in Austrian preschool children.
Methods:
1737 Austrian preschool children participated in a cross sectional questionnaire survey about passive smoking and the impact on wheezy bronchitis, asthma, hay fever and atopic dermatitis.
Results:
Up to 46% of the participating children were exposed to ETS at some stage in their life. Children of lower socioeconomic status were at exceptionally risk.ETS exposure during pregnancy resulted in a significantly increased risk for wheezing in the first year of life (OR 1.6; 95% CI 1.0-2.6), wheezing in the past 12 months (OR 1.5; 95% CI1.0-2.4) and doctor diagnosed asthma (OR 2.1;95% CI 1.0-4.1). Furthermore, breastfeeding and consumption of fruits and vegetables were less common in smoking families.
Conclusions:
Our study confirms previous studies, that in particular prenatal ETS exposure is a risk factor for wheezing and asthma in preschool children. Despite this, children exposed to ETS also live a "less healthier life" in terms of breast feeding and antioxidant intake. In the light of recent studies reporting increased oxidative stress in children exposed to passive smoking, the low intake of fruits and vegetables is a further concern.
More Related Videos
05:31Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
09:50Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
Related Concept Videos
Asthma-I: Introduction
Chronic Obstructive Pulmonary Disease-I: Introduction
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-III: Symptoms and Complications
Classification of Asthma
Other Pulmonary Disorders
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.