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Related Concept Videos

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...

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Bioinformatics data profiling tools: a prelude to metabolic profiling.

Natarajan Ganesan1, Bala Kalyanasundaram, Mahe Velauthapllai

  • 1Department of Computer Science, Georgetown University, 3900 Reservoir Rd NW Washington, DC 20057, USA.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
|November 10, 2007
PubMed
Summary

Metabolic profiling systematically analyzes cellular biochemical fingerprints. Bioinformatics tools integrate genetic and proteomic data, simplifying complex biological information discovery.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Systems Biology

Background:

  • Metabolic profiling involves characterizing cellular biochemical fingerprints.
  • Large datasets from cellular processes require advanced computational approaches.
  • Integrating genetic and proteomic data is crucial before metabolic profiling.

Purpose of the Study:

  • To highlight the role of computational biosciences in metabolic profiling.
  • To explain the function of bioinformatics profiling tools.
  • To demonstrate how these tools simplify data retrieval.

Main Methods:

  • Utilizing bioinformatics software for data compilation.
  • Developing user-friendly interfaces for data querying.
  • Searching multiple databases for genetic, RNA, and protein sequences.

Main Results:

  • Profiling tools aggregate information into standardized formats.
  • These tools reduce the need for extensive literature searches.
  • Simplified access to vast amounts of bioinformatics data is achieved.

Conclusions:

  • Bioinformatics profiling tools are essential for modern metabolic profiling.
  • These tools act as gateways to complex biological databases.
  • They streamline the process of information discovery in cellular processes.