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Hypocalcemic seizure due to congenital rickets in the first day of life
Omer Erdeve1, Begüim Atasay, Saadet Arsan
1Division of Neonatology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Insights
Congenital rickets, a rare newborn condition, can cause early-onset seizures due to vitamin D deficiency. Early recognition and treatment are crucial to prevent severe complications in newborns.
Area of Science:
- Neonatology
- Pediatric Endocrinology
- Nutritional Pediatrics
Background:
- Congenital rickets is a rare condition in newborns.
- Hypocalcemic seizures are a known complication, typically appearing after the first month of life.
Observation:
- This report details an unusual case of congenital rickets presenting with seizures on the first day of life.
- This highlights the potential for severe consequences of congenital rickets even at the earliest stage of life.
Findings:
- Despite advances in prenatal care, congenital rickets persists.
- Neonatal vitamin D deficiency, secondary to maternal deficiency, is a key consideration.
Implications:
- Pediatricians and neonatologists must consider congenital rickets in newborns presenting with early-onset seizures.
- Awareness of risk factors and prompt recognition of signs are vital for timely treatment and prevention of serious complications.
Abstract:
Congenital rickets is considered a rare disease entity in the newborn period. Hypocalcemic seizure due to congenital rickets has been reported, but this symptom generally appears at the earliest at the end of the first month of life. A congenital rickets case presented unusually with seizure on the first day of life is reported, and the continuing occurrence of the disease with serious consequences even at the beginning of life is emphasized. Despite improved prenatal care offered today, congenital rickets still occurs. It seems that vitamin D deficiency in the neonate secondary to maternal deficiency should be a consideration for the pediatrician or neonatologist caring for newborns. Physicians should be aware of risk factors that can trigger the development of this condition and should be alert to the signs of congenital rickets in order to commence appropriate treatment and prevent complications such as seizure occurring as early as shortly after birth.
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