Gingival infiltration in acute monoblastic leukaemia
Related Experiment Video
Updated: Jul 10, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
1Haematology SpR, West of Scotland Deanery. p_gallipoli@hotmail.com
Abstract:
Acute myeloid leukaemias (AML) are aggressive haematopoietic neoplasms that, if untreated, can lead to death within days. Up to 40% of presenting patients show evidence of extramedullary involvement (EMI) at diagnosis. EMI is reportedly most prevalent in myelo-monoblastic and monoblastic subtypes of AML (M4 and M5 according to FAB classification) and can present as leukaemic infiltrates in many sites including gingival enlargement and mucosal and skin nodules. We report a case of a patient who presented with gingival enlargement secondary to leukaemic infiltration. This case shows the importance of awareness of leukaemic infiltration as a cause for gingival enlargement.
Related Concept Videos
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Acute Inflammation II: Cellular Phase
Tonsillitis II: Management

